BACKGROUND Debridement is essential for successful wound management. Enzymatic debridement is commonly utilized in wound care but has been reported to be unsafe in wounds with significant bacterial bioburden, unless used in conjunction with topical antimicrobials. We examine this hypothesis with 2 commercially available, commonly used preparations of enzymatic debriding agents. MATERIALS AND ...

A universal public health issue that affects 60% to 90% of people worldwide is dental caries, especially in youngsters. Dental caries a cyclical event with phases demineralization and remineralization addition being continuous unidirectional process the mineral. Cavitation results from an overbalance process. While increasing ion deposition into crystal gaps demineralized enamel achieve net min...

Purpose: To summarize main findings of topical or transdermal preparation delivered in the skin eye region using novel nano-technology. Method: Narrative review all relevant papers from peer reviewed and high impact journals. Results: The delivery system pharmaceutical preparations for eyes are now elevated to aerosolized gels, foams, sprays other forms that nano-pharmaceutical dynamics such as...

BACKGROUND Napkin dermatitis (nappy or diaper rash) is a non-specific term used to describe inflammatory eruptions (rashes) in the napkin area. Most infants develop napkin dermatitis at least once during their infancy. Topical vitamin A has been suggested as a treatment for napkin dermatitis. OBJECTIVES To determine if treatment with topical vitamin A is successful in either preventing napkin...

The successful use of surgical and medical methods jaw bone tissue restoration has been convincingly confirmed in clinical practice. At the same time, technologies are being developed to improve osseointegration dental implants patients with osteoporosis. various implant coatings, as well systemic therapy, demonstrate emergence new directions treatment partial or complete secondary edentulism c...

HIV is transmitted to 6.4 million human beings per year and the majority of these transmissions are sexual. Condoms are highly effective and are recommended as the primary preventive. However, the fact that there are millions of sexual transmissions each year indicates that many people do not use condoms and that additional preventives are needed. The mechanisms of natural prevention of oral tr...

Treatment non-adherence is a complex problem encountered in all therapy areas, particularly in chronic diseases such as psoriasis vulgaris. To address adherence issues, focus is turning towards developing interventions tailored to individual patient needs. Topical therapies remain the mainstay of psoriasis treatment; however, these are associated with additional challenges where preparations ma...

The aim. To identify the factors influencing in vitro release of dexpanthenol (DP) from solutions and semi-solid preparations.
 Materials methods. Dispersed systems containing 5.0 % DP were studied: that Newtonian liquids preparations (creams, gels ointment) with non-Newtonian flow behaviour. Rheological studies performed by rotational viscometry. In tests using vertical diffusion cells. c...