Two hundred and forty male Cobb broilers were used to study the reasons of causing ascites. The results showed that cold ambient temperature could induce ascites (33.89% vs. 2.50%) and significantly increase triiodothyronine (T3), but reduce thyroxine (T4) concentrations in plasma (p<0.05). The ascitic broilers had high concentrations of aldosterone and K , but low concentrations of T3 and T4 i...

Here, we present a case of chronic myeloid leukemia for which imatinib therapy was initated. Triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone was normal, and thyroid microsomal autoantibodies (TMA) were positive and patient was diagnosed as thyroiditis treated with corticosteroids for 1½ months which lead to resolution.

Concerns have been raised over the use of iodine for disinfecting drinking water on extended space flights. Most fears revolve around effects of iodide on thyroid function. iodine (I2) is the form used in drinking-water disinfection. Risk assessments have treated the various forms of iodine as if they were toxicologically equivalent. Recent experiments conducted in rats found that administratio...

BACKGROUND Guinea pigs (Cavia porcellus) are often presented as patients in veterinary practice. Nevertheless, only limited information is available about endocrine diseases or thyroxine reference values for the species. OBJECTIVE The aim of this study was to determine serum thyroxine concentrations in a well-defined population of clinically healthy pet guinea pigs. METHODS Between October ...

Thyroid hormone [l-thyroxine (T4)] rapidly induced phosphorylation and nuclear translocation (activation) of mitogen-activated protein kinase (MAPK) in HeLa and CV-1 cells in the absence of cytokine or growth factor. A pertussis toxin-sensitive and guanosine 5'- O-(3-thiotriphosphate)-sensitive cell surface mechanism responsive to T4 and agarose-T4, suggesting a G protein-coupled receptor, was ...

A 55-year-old female was referred with abnormal thyroid function tests (TFTs); the free thyroxine level (FT4) was undetectable <3.3 pmol/L (normal: 7.9-14.4), while her FT3, TSH and urinary iodine levels were normal. She was clinically euthyroid with a large soft lobulated goitre that had been present for more than thirty years. She received an injection of recombinant human TSH (rhTSH) followi...

of the thyroid gland, a reasonable choice of therapy would be to try to correct the alteration in the immune system that initiated the disease. However, this therapeutic approach has yet to be perfected. Therefore, the alternative course of treatment of Graves’ disease is to control the excessive production and release of the thyroid hormones, thyroxine (T4) and triiodothyronine (T3), from the ...

this work analyzes the effects of satureja khuzestanica essential oil (skeo) on the thyroid and antioxidant system, assessed by measuring levels of tri-iodothyronine (t3), thyroxine (t4), thyroid-stimulating hormone (tsh), malondialdehyde (mda), reduced glutathione (gsh), and glutathione peroxidase (gpx) activity. forty adult male sprague dawley rats (225 ± 25 g) were divided into five equal gr...

and hypertension. Annual report of the American Association of Poison Control Centers' National Poison Data System of 2008 revealed that out of 9,006 unique exposures to thyroid preparations only 3 cases had major adverse outcome and there were no deaths[4]. It has been documented that there is no correlation between the amount of levothyroxine ingested and the onset and severity of the symptom...