Vaccine-mediated prevention of primary HIV-1 infection at the heterosexual mucosal portal of entry may be facilitated by highly optimised formulations or drug delivery devices for intravaginal (i.vag) immunization. Previously we described hydroxyethylcellulose (HEC)-based rheologically structured gel vehicles (RSVs) for vaginal immunization of an HIV-1 vaccine candidate, a soluble recombinant t...

BACKGROUND Nested nucleic acid amplification tests are often thought too sensitive or prone to generating false positive results for routine use. The current study investigated the specificity and clinical utility of a routine multiplex nested assay for mucosal herpetic infections. METHODS Ninety patients, categorised into those clinically diagnosed to (a) have and (b) not have herpetic infec...

AbstractIntroduction: Hyperplastic polyps of the esophago-gastric junction are seen during endoscopic evaluation of upper gastrointestinal tract. They are usually asymptomatic and discovered accidentally during endoscopic evaluation for other problems. These protrusions are mucosal regenerative response to surrounding mucosal injury. Case: Here we present a 9-year-old boy presenting with abdomi...

Plasma cell gingivitis, an infrequent benign entity, is inflammatory or reactive condition of the gingiva to certain allergens unknown factor. It clinically characterized by erythematous, edematous, granular/cobblestone appearance gingival surfaces with clear demarcation from mucogingival junction. easily bleeds on manipulation and may be associated a burning sensation spicy food consumption. A...

the objective of this study was to highlight the postnatal development of the uterine tubes of the west african dwarf goat from birth to 28 weeks of age by gross examination and light microscopy. there was a caudal migration of the paired uterine tubes from behind the paired kidneys at birth to the pelvic inlet at week 8 of age. each uterine tube exhibited three segments namely; infundibulum, a...

background: this study aimed to compare intermittent intravenous (iv) pantoprazole and ranitidine for control of gastric acid secretion and the possible prevention of upper gastrointestinal bleeding (ugib) in critical care patients. methods: this was a randomized, double blind clinical trial study of iv pantoprazole (40 mg every12 hour) or intermittent iv ranitidine (50 mg bolus every 8 hour) i...

BACKGROUND Lymph node metastasis (LNM) has been shown to be related to the prognosis of early gastric cancer (EGC). The choice of optimal treatment depends on an accurate pre-operative assessment of LNM status in EGC patients. However, in China, where EGC cases account for only a small part of gastric cancer (GC) cases, there are not enough data to make an accurate assessment. Therefore, this s...

UNLABELLED In patients who had previously undergone ileocolic resection due to Crohn's disease (CD) complications, anastomotic recurrence is a frequent event, which may lead to further surgical interventions. Optical colonoscopy with retrograde ileoscopy is currently the reference standard technique to confirm the clinical suspicion of anastomotic recurrence; however, the ileal side of ileocoli...

increased number of mast cells at the site of infection is widely regarded as important host defense against parasites. the kinetics of mucosal mast cells and connective tissue mast cells responses were studied in the intestines of 68 female cflp mice infected with 100 schistosoma mansoni cercariae. the number of mucosal mast cells and the connective tissue mast cells increased from week 3 and ...