A group of autoimmune diseases is characterised by autoantibodies against epithelial adhesion structures and/or tissue-tropic lymphocytes driving inflammatory processes resulting in specific pathology at the mucosal surfaces and the skin. The most frequent site of mucosal involvement in autoimmune diseases is the oral cavity. Broadly, these diseases include conditions affecting the cell-cell ad...

Pemphigus is a group of potentially life-threatening autoimmune diseases characterized by cutaneous and/or mucosal blistering. Pemphigus vulgaris (PV), the most common variant, is characterized by circulating IgG antibodies directed against desmoglein 3 (Dsg3), with about half the patients also having Dsg1 autoantibodies.There is a fairly strong genetic background to pemphigus with linkage to H...

Diseases and symptoms of mouth mucosa are prevalent in particular in the ageing populations. For example, a nationwide representative examination in the US revealed approximately 28% prevalence of all oral mucosal lesions in subjects 17 years of age and older with distinct differences between age groups and whether or not the subject smoked [27]. There are no comprehensive epidemiological data ...

OBJECTIVE Evidence for a connection between stress and selected neurodegenerative diseases as well as mental disorders is analyzed. Does stress cause or exacerbate related pathophysiological disease processes? METHOD The stress phenomenon is illustrated and the impact of stress on the nervous system, neurodegenerative diseases, and mental disorders is examined. The connection between stress a...

background: there is long-term interest in the effects of stress on health, due to the strain that it places on individuals which can lead to an increased risk of disease. the present study examined degree of perceived job stress related to incidents reporting rate and its dimensions among workers' isfahan steel company. methods: a self-administered anonymous was distributed to 189 workers. the...

METHODS The authors conducted a prospective observational study comparing salivary lactoferrin and lysozyme concentration over 5 months (chronic changes) in elite rowers (n=17, mean age 24.3+/-4.0 years) with sedentary individuals (controls) (n=18, mean age=27.2+/-7.1 years) and a graded exercise test to exhaustion (acute changes) with a cohort of elite rowers (n=11, mean age 24.7+/-4.1). RES...