Endothelial cells (ECs) are key participants in angiogenic processes that characterize tumor growth, wound repair, and inflammatory diseases, such as human rheumatoid arthritis (RA). We and others have shown that EC molecules, such as soluble E-selectin, mediate angiogenesis. Here we describe an EC molecule, Lewisy-6/H-5-2 glycoconjugate (Ley/H), that shares some structural features with the so...

Objective—The inhibition of oxidative stress is among the most relevant pleiotropic effects of statins. The mechanism by which statins exert their antioxidant effect in vivo is still undefined. NADPH oxidase is among the most important sources of reactive oxygen species involved in atherosclerotic disease. Methods/Results—We developed an ELISA to evaluate serum levels of soluble-gp91, the catal...

Soluble antigens of Haemophilus influenzae type b, Streptococcus pneumoniae, Neisseria meningitidis, and group B streptococcus were looked for in cerebrospinal fluid, serum, and urine by using the staphylococcal coagglutination test, latex agglutination test, and counterimmunoelectrophoresis. The staphylococcal coaggultination and latex agglutination tests were more sensitive than counterimmuno...

in vitro lymphocyte responses of high responder (hr) and low responder (lr) guinea pigs from pe-ripheral blood lymphocytes (pbl) to parasite antigens soluble protein third stage larvae (spl3) and soluble protein adult stage ( spa), non-parasite antigen ovalbumin (ova) were examined. there was substantial differences between hr and lr guinea pigs in the rate of acquisition of responsiveness to t...

A group G has subnormal deviation at most 1 if, for every descending chain H0 > H1 > . . . of non-subnormal subgroups of G, for all but finitely many i there is no infinite descending chain of non-subnormal subgroups of G that contain Hi+1 and are contained in Hi. This property P, say, was investigated in a previous paper by the authors, where soluble groups with P and locally nilpotent groups ...

We study the definability of certain subgroups of a group G that does not have the independence property. If a (type) definable subset X of an elementary extension G of G has property P , we call its trace X∩G over G an externally (type) definable P set. We show the following. Centralisers of subsets of G are externally definable subgroups. Cores of externally definable subgroups and iterated c...

Computer based techniques for recognizing finitely presented groups are quite powerful. Tools available for this purpose are outlined. They are available both in stand-alone programs and in more comprehensive systems. A general computational approach for investigating finitely presented groups by way of quotients and subgroups is described and examples are presented. The techniques can provide ...