The reductone ascorbic acid, present in the crystalline lens in concentrations higher than those of glucose, is capable of undergoing nonenzymatic "browning" in the presence of lenticular proteins. We studied the nonenzymatic browning with ascorbate in model systems employing bovine serum albumin and lens crystallins. When bovine serum albumin, alpha-crystallin, or gamma-crystallin was incubate...

OBJECTIVE To examine prospectively the association between dietary intake of vitamins C and E, carotene, and riboflavin and cataract extraction in women. DESIGN Prospective cohort study beginning in 1980 with eight years of follow up. SETTING 11 states of the United States. PARTICIPANTS Female registered nurses who were 45 to 67 years of age. 50,828 women were included in 1980 and others ...

By administering fluorescein intravenously to 95 patients we calculated the ratio of fluorescein concentration in the vitreous at the time of its peak level compared with the estimated unbound concentration of fluorescein in the plasma at the same time. We studied 12 normal phakic and 83 aphakic eye approximately two months, one year, and more than two years after cataract extraction. All the e...

Purpose: To quantitatively evaluate cataract surgeries performed between 2000 and 2005 at Farabi Eye Hospital, Tehran University of Medical Sciences Methods: This retrospective study aimed at patients who had cataract and underwent surgery at Farabi Eye Hospital, Tehran from 2000 to 2005. One week per season per year was randomly selected after excluding the first two weeks of the Persian Year ...

PURPOSE To determine the effect of cataract type and severity in eyes with pure types of age-related lens opacities on visual acuity (VA) and contrast sensitivity in the presence and absence of glare conditions. METHODS Sixty patients with senile cataracts aged 40 years or older with no other ocular pathologies were evaluated for VA and contrast sensitivity with and without glare. Lens opacit...

BACKGROUND Dietary antioxidants, including carotenoids, are hypothesized to decrease the risk of age-related cataracts by preventing oxidation of proteins or lipids within the lens. However, prospective epidemiologic data concerning this phenomenon are limited. OBJECTIVE Our objective was to examine prospectively the association between carotenoid and vitamin A intakes and cataract extraction...

as the stage next to that of corneal section and iridectomy in the extraction of a hard cataract; and I believe that this rule is invariably followed by the ophthalmic surgeons of the present day. The modification I propose, and have adopted in all my late cases, is to tear the capsule of the lens as the first preliminary step in the operation for extraction of cataract. The advantages accruing...