Background: Ionizing radiation causes deleterious effects on living system mainly due to oxidative damages of macromolecules and protein is the major target due to its abundance. The aim of this study was to investigate the effects of ionizing radiation induced changes in the molecular properties of bovine serum albumin (BSA) its secondary and tertiary structures, degradation, cross linking and...

background: to investigate the effect of zinc sulphate for prophylaxis of radiation-induced oral mucositis in patients with head and neck cancer. materials and methods: in the department of radiation oncology, ankara numune education and research hospital, 40 patients with head and neck cancer were selected randomly to receive either zinco-c 25 mg, four tablets daily or control group who did no...

BACKGROUND Silibinin has been known for its role in anti-cancer and radio-protective effect. Radiation therapy for treating lung cancer might lead to late-phase pulmonary inflammation and fibrosis. Thus, this study aimed to investigate the effects of silibinin in radiation-induced lung injury with a mouse model. METHODS In this study, we examined the ability of silibinin to mitigate lung inju...

Background: Radiation-induced cardiac events and pneumonitis are the major late radiotherapy side effects. Methods: We explored differences in dose distribution between 3D CRT, IMRT VMAT 125 women with unilateral breast cancer. The various to tumor OARs were studied for left right sided irradiation. Results: Upon using CRT breasts lymph nodes, we observed a significant increase ipsilateral lung...

Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to spread or metastasize throughout the body. In recent years, remarkable progress has been made toward the understanding of proposed hallmarks of cancer development, care, and treatment modalities. Radiation therapy or radiotherapy is an important and integral component of cancer management, mostly conf...

Hormone refractory human prostate cancer cell lines are known to be radioresistant, a feature attributed to their ability to induce anti-apoptotic proteins of the Bcl-2 family when exposed to radiation. We investigated whether pro-apoptotic compounds such as methyl jasmonate, a plant stress hormone, can counteract the radiation-induced anti-apoptotic mechanism in a human prostate cancer cell li...

The increase in risk for late-onset thyroid cancer due to radiation exposure is a potential health effect after a nuclear power plant accident mainly due to the release of radioiodine in fallout. The risk is particularly elevated in those exposed during infancy and adolescence. To estimate the possibility and extent of thyroid cancer occurrence after exposure, it is of utmost importance to coll...