نتایج جستجو برای: protective antigen

تعداد نتایج: 307620  

Journal: :Antimicrobial agents and chemotherapy 1991
J M Boggs N H Chang A Goundalkar

The effects of free amphotericin B (as Fungizone) and amphotericin B (AMB) incorporated into liposomes on the proliferation of lymphocytes were determined. Freshly obtained guinea pig and rat antigen-specific lymphocytes were compared with rat T-lymphocyte cell lines cultured for a long period of time. Incorporation of AMB into multilayered vesicles significantly reduced its effect relative to ...

2016
David J Gasper Brandon Neldner Erin H Plisch Hani Rustom Emily Carrow Hirotaka Imai Yoshihiro Kawaoka M Suresh

CD8+ cytotoxic T lymphocytes (CTLs) are critical for clearing many viral infections, and protective CTL memory can be induced by vaccination with attenuated viruses and vectors. Non-replicating vaccines are typically potentiated by the addition of adjuvants that enhance humoral responses, however few are capable of generating CTL responses. Adjuplex is a carbomer-lecithin-based adjuvant demonst...

Journal: :Proceedings of the National Academy of Sciences 2005

Journal: :Vaccine 2002
E D Williamson A M Bennett S D Perkins R J Beedham J Miller L W J Baillie

The protective antigen (PA) of Bacillus anthracis and the V antigen of Yersinia pestis are potent immunogens and candidate vaccine sub-units. When plasmid DNA encoding either PA or V antigen was used to immunise the Balb/c mouse, a low serum IgG titre was detected (log (10)1.0 or less) which was slightly increased by boosting with plasmid DNA. However, when mice immunised with plasmid DNA were ...

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