The literary structure of the Epistle to the Hebrews is uniquely complex. In a writing so multifaceted, where topics are foreshadowed and repeated, differences of opinion must inevitably arise regarding the precise divisions of the argument. This essay examines three specific approaches to the structure of Hebrews: the traditional view, which divides the epistle into doctrinal and practical par...

Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50-80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryos to address the hypothesis that blastomere behaviour may reflect ploidy during the first two cle...

Like animals, plants use asymmetric cell divisions to create pattern and diversity. Due to a rigid cell wall and lack of cell migrations, these asymmetric divisions incur the additional constraints of being locked into their initial orientations. How do plants specify and carry out asymmetric divisions? Intercellular communication has been suspected for some time and recent developments identif...

Biobanks are key research infrastructures aimed at the collection, storage, processing, and sharing of high-quality human biological samples associated data for research, diagnosis, personalized medicine. The Biobank Translational Digital Medicine Unit European Institute Oncology (IEO) is a landmark in this field. collaborate with clinical divisions, internal external groups, industry, supporti...

We consider the transfer pricing decision for a multidivisional firm with an upstream division and multiple downstream divisions. The downstream divisions can independently determine their retail prices, and decide on whether or not they will purchase from the upstream division at negotiated transfer prices. To allocate the firm-wide profit between upstream and downstream divisions, we construc...

Cell divisions producing two daughter cells that adopt distinct fates are defined as asymmetric. In all organisms, ranging from bacteria to mammals, in which development has been studied extensively, asymmetric cell divisions generate cell diversity. Asymmetric cell divisions can be achieved by either intrinsic or extrinsic mechanisms (Fig. 1). Intrinsic mechanisms involve the preferential segr...

This paper studies optimal organization structures in multidivisional organizations with more than two divisions. The decisions of individual divisions need to be adapted to local conditions and also be coordinated. The needs for coordination are described by a coordination network. Information about local conditions is held by division managers who communicate strategically. Hierarchy is an or...