BACKGROUND/AIMS Transfusion dependent subjects are at a great risk of viral hepatitis infection. We aimed to evaluate the prevalence and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection among transfusion-dependent patients in Taiwan. METHODS A total of 140 patients (67 thalassemic patients, 70 hemophilic patients, two patients with hereditary spherocytosis...

BACKGROUND Transfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in health care systems with limited resources. The aim of the study was to determine the prevalence of transfusion-transmitted infections in blood donors and to evaluate the demog...

The aim of this study is to present the status of transfusion –transmitted infections among the apparently healthy donors so as to increase the awareness of complications of blood transfusion and make the clinicians more vigilant with regard to judicious use of blood. A total of 5008 units of donor’s blood was screened from January 2006 to December 2008 at blood bank of People’s Hospital, Bhopa...

The risks after homogeneous blood transfusion must be minimized in oral and maxillofacial surgery. The risks include infectious diseases such as posttransfusional hepatitis, adult T-cell leukemia (ATL), acquired immunodeficiency syndrome (AIDS), etc., incompatibility o hemotypes and antibody formation. Autotransfusion is the transfusion of blood of a patient back into himself. We applied autotr...

The relationship between the presence of antibody to hepatitis B core antigen (anti-HBc) in donor blood and the development of hepatitis in recipients of that blood was studied in 6293 blood donors and 481 recipients who were followed for 6 to 9 months after transfusion. Of 193 recipients of at least 1 unit of blood positive for anti-HBc, 23 (11.9%) developed non-A, non-B hepatitis compared wit...

Iron overload and hepatitis virus C infection cause liver fibrosis in thalassemics. In a monocentric retrospective analysis of liver disease in a cohort of 191 transfusion-dependent thalassemics, in 126 patients who had undergone liver biopsy (mean age 17.2 years; 58 hepatitis virus C-RNA positive and 68 hepatitis virus C-RNA negative) the liver iron concentration (median 2.4 mg/gr dry liver we...

During the past 30 years great advances have been made in preventing what were the commonest forms of adverse transfusion reactions: namely pyrogenic reactions, circulatory overloading, haemolytic reactions and bacterial con­ tamination of donations. This has been achieved by the combined efforts of transfusion centres, hospital laboratories and clinical u sed of donor blood to promote safer tr...

Background: Hepatitis B is the most common blood-borne viral infection that is considered as a major public health problem of the world's major health problems. The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) infection among blood donors referring to blood transfusion centers. Methods: This retrospective cross-sectional study was performed on 216004 volunteer...