wnloaded creatic ductal adenocarcinoma (PDAC) is the most common pancreatic malignancy with a dismal osis. Developing novel strategies to prevent or delay pancreatic cancer is currently of intense intere chemopreventive efficacy of gefitinib, an epidermal growth factor receptor (EGFR) inhibitor, was ted against the progression of pancreatic intraepithelial neoplasms (PanIN) to PDAC in condition...

In this issue you will find an Opinion article by three icons of endometri-osis (Brosens et al., 2013). They present their ideas on the early stages of disease, in adolescents. Although there exists very little robust evidence to support many of their claims (as they recognize themselves), we decided to publish their manuscript to draw attention to the complex issue of preventive reproductive h...

BACKGROUND Severe combined immunodeficiency is within a heterogeneous group of inherited defects throughout the development of T- and/or B-lymphocytes. Mutations in recombinase-activating genes 1 or 2 (RAG1/2) represent approximately 10% of all SCID cases. RAG1/2 are essential for V(D)J rearrangement of the B- and T-cell receptors. OBJECTIVES The aim of this study was to review clinical, immu...

ownload huosis is a unique form of nonapoptotic cell death triggered by alterations in the trafficking of clathrinndent endosomes, ultimately leading to extreme vacuolization and rupture of the cell. Methuosis can be d in glioblastoma cells by expression of constitutively active Ras. This study identifies the small GTPases, nd Arf6, and the Arf6 GTPase-activating protein, GIT1, as key downstrea...

The dynamics of social, national and state life continue to develop along with the development phenomena, science, technology. Nowadays, problems appear in form various phenomena that can be said actual, but clichéd. In world education, recently, for example, several viral news have appeared mass media social about clichés, namely intolerance. News or issue intolerance, is a recorded conversati...

The purpose of this study is to find out the use social networks that are used as a medium for forming personality good citizens at SMKN 4 Padalarang. Knowing steps in networking media form character citizen. role This research uses qualitative approach with methods using case methods. results show taken by PKN teachers so Facebook can be means interaction students, usually TKJ and OSIS create ...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Papillary cystadenoma (PC) is an epithelial tumor believed to be of mesonephric origin 1 th...

Near-death experiences, profound subjective events experienced on the threshold of death, have been extensively studied over the past decade. These near-death experiences (NDEs) often include events with apparently paranormal features. In one study (Greyson & Stevenson, 1980), 75% of subjects reported out-of-body experiences, 49% reported an apparitional experience, 39% reported apparent extras...