Swellings over the upper and lower limbs were encountered in a one-year-old child. Skeletal survey showed a constellation of distinctive radiographic abnormalities of osteoporosis, hyperplastic callus and ossification of the interosseous membrane of the forearm, femora, and to lesser extent the tibiae. Neither wormian bones of the skull nor dentinogenesis imperfecta was present. Genetic tests r...

amelogenesis imperfecta is a heterogeneous group of hereditary disorders. its treatment continues throughout the patients' childhood and adolescence and consists of advanced restorative care in severe cases. a thorough prosthodontic treatment plan including orthognatic surgery, full veneer crowns and all ceramic anterior crowns is presented in this clinical report.

Background: Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and multiple fractures. Approximately 90% are caused mutation in COL1A1 or COL1A2 genes, the disease transmitted either autosomal dominantly recessively appears as spontaneous mutation. Protein product of these two genes type I collagen, major structural protein skin, which affected quality,...

La cultura de la violencia se ha internalizado en las formas pensar, hablar, actitudes y comportamientos Escuela, es ejercida hacia los niños, niñas, por lo que hace necesario promover paz estrategia fundamental. Paz interior el fundamento este estudio, un estado serenidad armonía perdurable e inalterable trasforma a persona desde su interior, sustenta virtudes. Y Imperfecta reconoce conflicto ...

Osteogenesis imperfecta (OI), also known as "brittle bone disease", is a rare genetic disorder of the skeleton, whose most benign form I corresponds to autosomal dominant mutations in genes encoding type collagen (COLA1, COLA2). Several associated skeletal manifestations are often observed but, surprisingly, while dentin defects reflect disorders, about half OI patients have no obvious oral man...

manifestations that are regarded nontypical for the full-blown disease. Case report A 35-year-old G2P1 Caucasian woman had her first-trimester ultrasound evaluation. The histological picture was typical of osteogenesis imperfecta type II/III. The combination of severe distortion of the limb bones with rib and limb fractures, in association with the above histopathology, permitted the diagnosis ...

The diagnosis of Amelogenesis Imperfecta (AI) in a young patient can present many complex restorative and orth odontic challenges for the pediatric dentist. These patients have traditionally been treated with a combination of extractions, composite bonding, stainless steel crowns, adhesive castings, over-dentures, and porcelain veneers. They often have anterior open bites or vertical deep bites...

The correct distinction between osteogenesis imperfecta and non-accidental injury (NAI) is an emotive subject upon which the fate of a child can depend. It has been the subject of strongly worded papers and letters by experts. 1-5 Although the frequency, clinical features, and skeletal effects of NAI are not in question, much new knowledge on osteogenesis imperfecta has bypassed the general pae...

Osteogenesis imperfecta (OI) is a group of genetic heterogeneous connective tissue disorders characterized by increased bone fragility and susceptibility to fractures. Laboratory diagnosis relies on time-consuming and cost-intensive biochemical and molecular genetics analyses. Therefore, it is desirable to identify and establish new diagnostic markers for OI that are reliable, cost-effective an...