adenotonsillar hypertrophy and obstructive sleep disordered breathing can lead to attention deficit/hyperactivity disorder (adhd). the purpose of this study was to evaluate effect of adenotonsillectomy on improvement of adhd symptoms in a quasi-experimental (before and after) study. the efficacy of adenotonsillectomy on improvement of adhd symptoms of 35 children aged 5-12 years with adenotonsi...

background since adenoids may act as a reservoir for bacteria, they can cause ear infection, recurrent otitis and recurrent adenotonsillitis. therefore, adenotonsillectomy is an efficient method for reducing the number and severity of subsequent infections. objectives this study aimed to determine the chlamydophila pneumonia infection by serological tests and performing pcr in the adenoid tissu...

Abstract Background Cardiac hypertrophy precedes many heart diseases and understanding its molecular basis remains one of the greatest challenges in cardiovascular medicine. Recent studies highlighted sporadic involvement long noncoding RNAs (lncRNAs) cardiac development disease but our lncRNAs failure is still limited. Results Expression profiling failing mouse hearts revealed dysregulation “B...

Significance: Heart failure, a disease with extremely high incidence, is closely associated inflammation and oxidative stress. The Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) pathway plays an important role in the occurrence development of heart failure. Recent advances: Previous studies have shown that TLR4/NF-κB causes failure by inducing stress inflammation; damaging endotheli...

we aimed to investigate the correlation of tonsillectomy with palatine tonsil size and to compare the differences of tonsil size and the need for surgery in children and adults. also we can predict the outcome of tonsillectomy. we measured tonsil sizes in (height and width) in 150 children and 35 adults with hypertrophy of palatine tonsils and we measured the mass of tonsils and then the data a...

Cell differentiation degree and mitotic activity were sequentially assessed by immunoperoxidase labeling of glial fibrillary acidic protein (GFAP) and proliferative cell nuclear antigen (PCNA), respectively, in rat brain cultured astrocytes maintained up to 60 days in vitro (DIV) of first subculture, or weekly passaged until their 12th subculture. Cell count was performed through a 0.01 mm2 sec...

background:gastroesophageal reflux disease (gerd) prevalence in patients with sulfur mustard (sm)-induced bronchiolitis obliterans (bo) is higher than exposed cases with mild lung injuries. in this study, we aimed to evaluate the prevalence of microaspirations using nuclear scintiscan among bo patients with sm exposure. methods: this was a prospective cross-sectional study conducted on patients...

The role of Pygo1 in mammalian cardiac disease remains unelucidated. In this study, we found that is associated with human pathological hypertrophy. Cardiac-specific overexpression mice spontaneously led to hypertrophy, accompanied by declined function, increased heart weight/body weight and weight/tibial length ratios, cell size. Meanwhile, function was improved when expression interfered hype...

Beta-catenin is a transcriptional activator shown to regulate the embryonic, postnatal, and oncogenic growth of many tissues. In most research to date, beta-catenin activation has been the unique downstream function of the Wnt signaling pathway. However, in the heart, a Wnt-independent mechanism involving Akt-mediated phosphorylation of glycogen synthase kinase (GSK)-3beta was recently shown to...