This article deals with the problem of gastroesophageal reflux disease (GERD) in children, which has an enormous medical and social importance. Despite recent advances in therapy, the disease is characterized by recurrent exacerbations with the development of complications, which dictates the need of finding a new pathogenically supported esophagitis treatment. In this regard, the effectiveness...

Gastroesophageal reflux disease (GERD) is a chronic condition requiring long-term treatment. Simple lifestyle modifications are the first methods employed by patients and, because of their low cost and simplicity, should be continued even when more potent therapies are initiated. Potent acid-suppressive therapy is currently the most important and successful medical therapy. Whereas healing of t...

PURPOSE To develop experimental models to evaluate the effects of hydrochloric acid associated with the pepsin instilled in the mucosa of the upper esophagus and the esophagogastric junction of young male rats Wistar, simulating injury caused by gastroesophageal reflux on the mucosa of aero-digestive tract in humans as well as the action of the risk exposure of mucosa to cigarette smoke. METH...

Background and objectives: Gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .Hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...

OBJECTIVE The objective of this study was to investigate the effect of chronic constipation on children's quality of life. METHODS From October 2002 to November 2003, 224 children (140 male, 84 female, aged 10.6 +/- 2.9 years) and 224 parents were evaluated by a health related quality of life tool during initial outpatient consultation. Children with constipation (n = 80) were compared with c...

Received January 5, 2000 Abstract Gastroesophageal reflux (GER) is a common disease found in early childhood. It commonly presents with vomiting and feeding problems. However, it may involve other systems like respiratory system, growth failure. Twenty-four hours esophageal pH monitoring is a useful technique in diagnosis of gastroesophageal reflux. Results of 24 hours esophageal pH monitoring ...

introduction congenital microgastria is an extremely rare anomaly, which is due to failure of gastric development, and causes a tubular stomach with reduced capacity. it is almost always associated with other congenital anomalies. case presentation the patient was a two-month-old boy with microgastria in association with gastroesophageal reflux, tracheomalacia, and limb defect. discussion most ...

OBJECTIVE To develop a North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) international consensus on the diagnosis and management of gastroesophageal reflux and gastroesophageal reflux disease in the pediatric population. METHODS An international panel of 9 pediatr...