نتایج جستجو برای: nitric oxide synthase gene

تعداد نتایج: 1343326  

Journal: :Circulation research 2009
Wilfried Schgoer Markus Theurl Johannes Jeschke Arno G E Beer Karin Albrecht Roland Gander Song Rong Danijela Vasiljevic Margot Egger Anna Maria Wolf Silke Frauscher Bernhard Koller Ivan Tancevski Josef R Patsch Peter Schratzberger Hildegunde Piza-Katzer Andreas Ritsch Ferdinand H Bahlmann Reiner Fischer-Colbrie Dominik Wolf Rudolf Kirchmair

RATIONALE The neuropeptide secretoneurin induces angiogenesis and postnatal vasculogenesis and is upregulated by hypoxia in skeletal muscle cells. OBJECTIVE We sought to investigate the effects of secretoneurin on therapeutic angiogenesis. METHODS AND RESULTS We generated a secretoneurin gene therapy vector. In the mouse hindlimb ischemia model secretoneurin gene therapy by intramuscular pl...

Journal: :Gut 2000
P Kubes

The established dogma regarding the different isoforms of nitric oxide has been that constitutively expressed nitric oxide synthase is an extremely important homeostatic regulator of numerous important physiological processes whereas the inducible form of nitric oxide synthase underlies injury associated with intestinal inflammation. In this brief overview, I review some of the literature that ...

Journal: :iranian journal of basic medical sciences 0
khadije farrokhfall department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran mehri seyed hashtroudi department of marine living sciences, iranian national institute for oceanography and atmospheric sciences (inioas), tehran, iran asghar ghasemi endocrine physiology research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran hossein mehrani chemical injuries research center, baqiyatallah university of medical sciences, tehran, iran

objective(s):some pathologic situations such as diabetes and metabolic syndrome are associated with alternation in nitric oxide level. incidence of these condition increases with aging. on the other hand, insulin secretion is modulated by nitric oxide, and nitric oxide synthase (nos) activity is also altered in diabetes. in this study, modification in the enzyme activity associated with aging a...

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