نتایج جستجو برای: neuropeptides

تعداد نتایج: 9355  

Journal: :The Journal of experimental biology 1994
P D Evans

1. The modulatory actions of myomodulin A on tension generated in the extensortibiae muscle of the locust hindleg by stimulation of the slow excitatory motoneurone (SETi) depend upon the frequency of stimulation. Myomodulin A has no consistent effect on the tension induced by the fast extensor motoneurone (FETi) or upon the myogenic rhythm present in the extensor. The effects of a range of stru...

Journal: :Mediators of Inflammation 1997
J. D. Van Bergeijk J. H. P. Wilson

Intestinal inflammation is controlled by various immunomodulating cells, interacting by molecular mediators. Neuropeptides, released by enteric nerve cells and neuroendocrine mucosa cells, are able to affect several aspects of the general and intestinal immune system, with both pro- as well as anti-inflammatory activities. In inflammatory bowel disease (IBD) there is both morphological as well ...

2015
Marta Słoniecka Sandrine Le Roux Peter Boman Berit Byström Qingjun Zhou Patrik Danielson Alexander V. Ljubimov

Keratocytes, the quiescent cells of the corneal stroma, play a crucial role in corneal wound healing. Neuropeptides and neurotransmitters are usually associated with neuronal signaling, but have recently been shown to be produced also by non-neuronal cells and to be involved in many cellular processes. The aim of this study was to assess the endogenous intracellular and secreted levels of the n...

2004
Michael S. Cowen Feng Chen Andrew J. Lawrence

The role of neuromodulatory peptides in the aetiology of alcoholism has been relatively under-explored; however, the development of selective ligands for neuropeptide receptors, the characterization and cloning of receptors, and the development of transgenic mouse models have greatly facilitated this analysis. The present review considers the most recent preclinical evidence obtained from anima...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Liliane Schoofs Isabel Beets

The growth toward adulthood occurs mainly through one or several intermediate stages or larval forms. Driven by environmental and internal state cues, all animals undergo one or more transitions during their life, which are accompanied by changes in morphology, physiology, and behavior. Larval settlement in the annelid Platynereis dumerilii is a prime example of such a life-phase transition. In...

Journal: :Journal of Synthetic Organic Chemistry, Japan 1992

2018
Juhua Chang Jianhua Zhao Xiaoli Tian

Parasitoid wasps of the order Hymenoptera, the most diverse groups of animals, are important natural enemies of arthropod hosts in natural ecosystems and can be used in biological control. To date, only one neuropeptidome of a parasitoid wasp, Nasonia vitripennis, has been identified. This study aimed to identify more neuropeptides of parasitoid wasps, by using a well-established workflow that ...

Journal: :Cancer research 1992
P A Bunn D Chan D G Dienhart R Tolley M Tagawa P B Jewett

To define the role of neuropeptides in lung cancer biology, we evaluated the effect of seven peptide classes on signal transduction and growth in human lung and breast cancer cell lines. Flow cytometric methods were used to quantitate the calcium response in individual cells produced by these peptides alone or in combination. The effects on growth were assessed by [3H]thymidine, 3-(4,5-dimethyl...

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