UNLABELLED The use of natural substances and micronutritional approaches has been suggested as a therapeutic alternative to benefit the bone healing associated with no side effects. Nevertheless, the influence of micronutritional interventions with therapeutic proprieties on the bone repair has yet to be intensely evaluated, and no evidence is available exploring the impact of micronutrient sup...

The fetus is more susceptible than the adult to the effects of certain carcinogens, such as polycyclic aromatic hydrocarbons (PAH). Nutritional factors, including antioxidants, have been shown to have a protective effect on carcinogen-DNA adducts and cancer risk in adults. We investigated whether the effect of prenatal airborne PAH exposure, measured by personal air monitoring during pregnancy,...

BACKGROUND Inverse associations between micronutrient intake and cardiovascular outcomes have been previously shown, but did not focus on diabetic patients. OBJECTIVE To systematically review the role of micronutrients in the development/presence of cardiovascular outcomes in patients with diabetes. METHODS We searched Medline, Embase, and Scopus (January/1949-March/2012) for observational ...

Micronutrients make up the central nervous system structure and play major functional roles: they stimulate nerve cell development, migration, and differentiation. The goal of this study is to review the scientific literature regarding the role of micronutrients in infant brain structure and function. Thus, we aim at providing pediatricians with knowledge on the importance of introducing all nu...

PURPOSE OF REVIEW Multiple micronutrient deficiencies are still common worldwide and often occur at an early age, negatively affecting both physical and cognitive development. Even though specific effects of a variety of different micronutrients have been studied extensively, it is understood that a combination of multiple micronutrients may be more beneficial in most instances, as deficiencies...

OBJECTIVE To assess the impact on birth size and risk of low birth weight of alternative combinations of micronutrients given to pregnant women. DESIGN Double blind cluster randomised controlled trial. SETTING Rural community in south eastern Nepal. PARTICIPANTS 4926 pregnant women and 4130 live born infants. INTERVENTIONS 426 communities were randomised to five regimens in which pregna...

OBJECTIVE Our objective was to evaluate the association of dietary intakes of selected micronutrients and blood lead (PbB) concentrations in female adults and in children. DESIGN With longitudinal monitoring, we measured daily intakes of the micronutrients calcium, magnesium, sodium, potassium, barium, strontium, phosphorus, zinc, iron (limited data), and copper from 6-day duplicate diets (2-...

BACKGROUND Multiple micronutrient deficiencies are common among women in low-income countries and may adversely affect pregnancy outcomes. OBJECTIVE To conduct a meta-analysis of the effects on stillbirths and on early and late neonatal mortality of supplementation during pregnancy with multiple micronutrients compared with iron-folic acid in recent randomized, controlled trials. METHODS Tw...

BACKGROUND Selenium is an essential trace element that is important for thyroid hormone metabolism and has antioxidant properties which protect the thyroid gland from oxidative stress. The association of selenium, as well as intake of other micronutrients, with thyroid cancer is unclear. METHODS We evaluated associations of dietary selenium, beta-carotene, calcium, vitamin D, vitamin C, vitam...

BACKGROUND & AIMS : We hypothesize that wound closure in trauma patients with disorders in wound healing is accelerated by supplementation of antioxidant micronutrients and glutamine. METHODS In a randomized, double-blind, placebo-controlled trial, 20 trauma patients with disorders in wound healing were orally supplemented with antioxidant micronutrients (ascorbic acid, α-tocopherol, β-carote...