Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has c...

Melissa officinalis (L.) (Lamiaceae), a plant known as the lemon balm, is native to the east Mediterranean region and west Asia. Also found in tropical countries, such as Brazil, where it is popularly known as "erva-cidreira" or "melissa", it is widely used in aqueous- or alcoholic-extract form in the treatment of various disorders. The aim was to investigate in vivo its antigenotoxicity and an...

BACKGROUND Melissa officinalis, an herbal drug, is well known and frequently applied in traditional and modern medicine. Yet, there is inadequate information regarding its effects on electrical properties of the heart. The present study attempted to elucidate the effects of Melissa officinalis aqueous extract on electrocardiogram (ECG) in rat. OBJECTIVES ECG is an easy, fast and valuable tool...

We prove Iqbal’s conjecture on the relationship between the free energy of closed string theory in local toric geometry and the Wess-ZuminoWitten model. This is achieved by first reformulating the calculations of the free energy by localization techniques in terms of suitable Feynman rule, then exploiting a realization of the Feynman rule by free bosons. We also use a formula of Hodge integrals...

Károly Mirnics,1,2* Zeljka Korade,3* Dominique Arion,1 Orly Lazarov,4 Travis Unger,1 Melissa Macioce,1 Michael Sabatini,1,2 David Terrano,4 Katherine C. Douglass,1 Nina F. Schor,3 and Sangram S. Sisodia4 Departments of 1Psychiatry, 2Neurobiology, and 3Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, and 4Center for Molecular Neurobiology, University of Ch...

Melissa M. Amick, PhD  the number of drivers over the age of 75 will dramatically increase over the next few decades. Adults age 85 and older have the highest rate of driver fatalities. Individuals age 70 and older have the greatest motor vehicle fatality rates per mile driven compared to all but the riskiest age group, those 25 years and younger. Advanced age is also a risk factor for motor v...

In no area of the social sciences has ideology contaminated knowledge more pervasively than in writings on the sex industry. Too often in this area, the canons of scientific inquiry are suspended and research deliberately skewed to serve a particular political agenda. Much of this work has been done by writers who regard the sex industry as a despicable institution and who are active in campaig...

The effect of blended instruction on accelerated learning Melissa M. Patchan, Christian D. Schunn, Wilfried Sieg & Dawn McLaughlin a Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, USA b Learning Research and Development Center, University of Pittsburgh, Pittsburgh, USA c Department of Philosophy, Carnegie Mellon University, Pittsburgh, USA Published onl...