Cardiovascular effects of total intravenous anesthesia using ketamine-medetomidine-propofol drug combination (KMP-TIVA) were determined in 5 Thoroughbred horses undergoing surgery. The horses were anesthetized with intravenous administration (IV) of ketamine (2.5 mg/kg) and midazolam (0.04 mg/kg) following premedication with medetomidne (5 µg/kg, IV) and artificially ventilated. Surgical anesth...

Thermometric data loggers were surgically implanted in 15 impala (Aepyceros melampus) to investigate the consequences of chemical capture. Impala were darted and chemically immobilised for 30 min with each of the following drug combinations: etorphine and azaperone; etorphine and medetomidine; thiafentanil and azaperone, and a thiafentanil medetomidine combination. During immobilisation, pulse ...

BACKGROUND This study assessed the effects of sedation using a combination of fentanyl, midazolam and medetomidine in comparison to ketamine. Rhesus Macaques (Macaca mulatta), (n = 16, 5 males and 3 females randomly allocated to each treatment group) received either ketamine (KET) (10 mg.kg(-1)) or fentanyl-midazolam-medetomidine (FMM) (10 μg/kg(-1); 0.5 mg.kg(-1); 20 μg.kg(-1)) both IM. Oxygen...

OBJECTIVE To compare the analgesic effects of buprenorphine and butorphanol in domestic cats. DESIGN 2-phase positive-controlled randomized masked clinical trial. ANIMALS 39 healthy female cats (10 in phase 1 and 29 in phase 2). PROCEDURES Cats admitted for ovariohysterectomy received buprenorphine (4 in phase 1; 14 in phase 2) or butorphanol (6 in phase 1; 15 in phase 2). In phase 1, cat...

An 11-year-old Holstein mare was referred after profuse bilateral epistaxis due to fungal plaques. Clinical evaluation unremarkable except for mild tachycardia. General anaesthesia induced coil embolisation of the left internal carotid artery, right external and maxillary arteries. Under anaesthesia, cardiorespiratory stability ensured, six coils were deployed under fluoroscopy, whereas three p...