The purpose of this study was to determine the concordance between two equations used for estimating glomerular filtration rate, in order to verify the possibility to be used interchangeably in the clinical practice. We present a retrospective study performed on a group of 258 patients with chronic kidney disease treated between January 2008 and December 2009 in the Department of Nephrology of ...

BACKGROUND Limited data suggest that HMG-CoA reductase inhibitors (statins) reduce rates of kidney function loss. We performed this analysis to determine whether pravastatin reduced the rate of kidney function loss over approximately 5 years in people with or at high risk for coronary disease. METHODS AND RESULTS This was a post hoc subgroup analysis of data from 3 randomized double-blind con...

BACKGROUND Renal dysfunction predicts increased mortality in cardiovascular patients, but the best renal estimator for quantifying risks is uncertain. We compared admission serum urea nitrogen (SUN) level, creatinine level, Modification of Diet in Renal Disease (MDRD) rate, and Mayo estimated glomerular filtration rate (eGFR) for predicting mortality. METHODS In a retrospective cohort of Medi...

Mục tiêu: Khảo sát mối liên hệ giữa một số xét nghiệm sinh hóa và thông học với chỉ lọc cầu thận thiết lập bởi các công thức Cockcroft – Gault, MDRD, CKD EPI 2009, độ thanh thải creatinine 24 giờ trên đối tượng suy mạn.Phương pháp nghiên cứu: Cắt ngang mô tả 44 người là dân Việt Nam, từ đủ 18 tuổi trở lên mắc bệnh mạn đến khám tại phòng Khám thận, Bệnh viện Đại Y Dược cơ sở 2.Kết quả: Độ tương ...

Glomerular filtration rate (GFR) estimates facilitate detection of chronic kidney disease. Performance of the Modification of Diet in Renal Disease (MDRD) Study equation varies substantially among populations. To describe the performance of the equation in a large, diverse population, estimated GFR (eGFR) was compared to measured GFR (mGFR) in a cross-sectional analysis of 5504 participants in ...

Background. Serum creatinine (Scr)-based equations lack accuracy in predicting glomerular filtration rate (GFR) in patients with liver disease. Cimetidine has been shown to improve the performance of Scr-based GFR formulae. Methods. We evaluated the use of cimetidine on the performance of GFR-estimating equations in 39 liver transplant recipients. The patients received oral cimetidine (800 mg t...

BACKGROUND The prevalence of stage 3 chronic kidney disease (CKD) is increasing, calculated using the modification of diet in renal disease (MDRD) study equation for estimating glomerular filtration rate (GFR). Cystatin C-based equations are also being used to estimate GFR. Using creatinine-based and cystatin C-based equations, the aim of our study was to measure the difference in prevalence of...

BACKGROUND Antiretrovirals (ARVs) could lead to clinically significant nephrotoxicity and as such will require dose adjustments in the presence of renal insufficiency. OBJECTIVE To explore renal function estimating equations as alternatives for glomerular filtration rate (GFR) measurement in a stable cohort of HIV-infected patients. METHOD In estimating renal insufficiency in Ghanaian HIV-i...

In patients with resistant hypertension (RH) we investigated the importance of urinary neutrophil gelatinase-associated lipocalin (uNGAL- a chemiluminescent microparticle immunoassay (CMIA) method became using (Abbott Diagnostics) for the measurement of NGAL in urine samples) and incidence of chronic kidney disease using the Modification of Diet in Renal Disease Study (MDRD) and Chronic Kidney ...

INTRODUCTION Assessment of glomerular filtration rate (GFR) is the best index of kidney functions. We aimed to determine the accuracy of El-Minia equation for estimation of GFR in different stages of chronic kidney disease (CKD) in the El-Minia population of CKD patients, in comparison to other proposed equations. MATERIALS AND METHODS The study included 320 isotopic GFR measurements by 99m-T...