Our understanding of the pathogenesis and heterogeneity of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) has been dramatically enhanced by recent attempts to profile molecular features of these lymphomas. In this article, we discuss ways in which testing for molecular features may impact DLBCL and FL management if clinical trials are designed to incorporate such tests. Spec...

It is extremely unusual for primary pulmonary lymphoma, an uncommon occurrence in any form, to be of T-cell origin and manifest as endobronchial lesion. Each these characteristics rare individually, so cases that combine them are exceptional. We report a patient whom anaplastic large cell neoplasm, presented with obstruction the left upper lobe bronchus, resulting atelectasis creating radiograp...

background : there are only a few reports that exist regarding primary non-hodgkin lymphoma of the genital tract. in this article, one case of primary b-cell type non-hodgkin lymphoma (nhl) of the cervix is presented. case history: a 45 year-old woman presented bloody vaginal  discharge. upon vaginal examination, the cervix was found to be enlarged. cervical biopsy revealed b-cell type non-hodg...

non-hodgkin lymphoma is very uncommon in infancy and skin as the primary site of involvement in non-hodgkin lymphoma is rarely encountered. we describe a 10-month-old infant with t-cell non-hodgkin lymphoma who presented with multiple skin nodules as the predominant feature of her disease. the clinical manifestations, treatment strategy and disease outcome are reviewed. key words: non-hodgkin l...

Comparison and exploration of the prognostic value advanced lung cancer inflammation index, nutritional systemic immune-inflammation index in newly diagnosed diffuse large B-cell lymphoma

BACKGROUND Gene expression profiling has successfully identified the prognostic significance of the host response in lymphomas. The aggressive T-cell/histiocyte-rich large B-cell lymphoma and the indolent nodular lymphocyte-predominant Hodgkin's lymphoma are both characterized by a paucity of tumor cells embedded in an overwhelming background. The tumor cells of both lymphomas share several cha...