نتایج جستجو برای: killer cells

تعداد نتایج: 1392378  

Journal: :Frontiers in Immunology 2013

Journal: :Journal of Innate Immunity 2011

Journal: :Clinical Immunology and Immunopathology 1988

Journal: :Cancer Discovery 2021

Abstract Summary: Natural killer (NK) cells accumulate at the fetal–maternal interface and represent 70% of immune in decidua (dNK) first-trimester pregnancy; they are immune-tolerant toward semiallogenic fetus “nurturing” nonkilling NK cells. A subset patients with cancer have features common dNK, which include expressing CD56, CD9, CD49a, CXCR3, being poorly cytotoxic proangiogenic, mimicking...

2017
Junyong Zhang Nian Wu Zhengrong Lian Huyi Feng Qing Jiang Xianfeng Chen Jianping Gong Zhengrong Qiao

The combination of radiotherapy and immunotherapy has shown great promise in eradicating tumors. For example, 125I radioactive particle implantation and cytokine-induced killer cell therapies have demonstrated efficacy in treating hepatocellular carcinoma. However, the mechanism of this combination therapy remains unknown. In this study, we utilized cytokine-induced killer cells obtained from h...

Journal: :Haematologica 2012
J Luis Espinoza Akiyoshi Takami Katsuji Yoshioka Katsuya Nakata Tokiharu Sato Yoshihito Kasahara Shinji Nakao

BACKGROUND NKG2D is an activating receptor expressed by natural killer and T cells, which have crucial functions in tumor and microbial immunosurveillance. Several cytokines have been identified as modulators of NKG2D receptor expression. However, little is known about NKG2D gene regulation. In this study, we found that microRNA 1245 attenuated the expression of NKG2D in natural killer cells. ...

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