PURPOSE To report a case of Coats' disease managed with the dexamethasone intravitreal implant Ozurdex(®) (Allergan, Inc., Irvine, Calif., USA) combined with retinal photocoagulation. METHODS A 46-year-old female with 20/200 visual acuity was diagnosed with Coats' disease with secondary retinal vasoproliferative tumor. An initial approach was performed with an intravitreal injection of the su...

The Purpose of this study was to evaluate the efficacy of IVTA as rescue therapy in patients with DME refractory to intravitreal ranibizumab. This is a prospective interventional non-comparative study that included diabetic patients with persistent CSME and associated visual loss despite previous treatment with intravitreal ranibizumab. Main outcome measures were improvement of BCVA 3 Snellen l...

PURPOSE To evaluate the efficacy and safety of photodynamic therapy (PDT) with verteporfin combined with intravitreal triamcinolone (IVTA) in occult choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). DESIGN Single center, nonrandomized interventional case series. METHODS A prospective, noncomparative, interventional case series of 41 eyes of 41 patients ...

Background: Post-operative endophthalmitis remains one of the most visually devastating complications of cataract surgery. Cluster endophthalmitis is defi ned as fi ve or more cases of endophthalmitis occurring on a particular day in a single operating room in one centre. Excessive infl ammation, particularly in the early post-operative phase, should be regarded as infective endophthalmitis. Ea...

AIM To evaluate the efficacy of intravitreal dexamethasone co-administered with intravitreal antibiotics along with vitrectomy in the management of exogenous bacterial endophthalmitis. METHODS In a prospective randomised clinical trial, 63 patients (63 eyes) with suspected bacterial endophthalmitis (postoperative and post-traumatic) were treated with vitrectomy and intravitreal antibiotics an...

UNLABELLED Purpose To investigate the elimination rate of voriconazole after intravitreal injection in rabbits. METHODS Intravitreal injections of 35 microg/0.1 mL voriconazole were administered to rabbits. Vitreous and aqueous humor levels of voriconazole were determined at selected time intervals (1, 2, 4, 8, 16, 24, and 48 hours), and the in vitreous half-life was calculated. Four to six e...

Dear Editor, The recent report on “Intravitreal Bevacizumab in Vitreous Hemorrhage and DM” is very interesting.1 Alagöz et al.1 noted that “intravitreal bevacizumab was found effective in cases with vitreous hemorrhage secondary to proliferative diabetic retinopathy in terms of reducing the need for surgery and increasing the rate of subjects to whom panretinal photocoagulation could be applied...