UNLABELLED Aims/Introduction:  Insulin therapy is often required to achieve good glycemic control in patients with type 2 diabetes mellitus. However, some providers, particularly general practitioners (GPs), are reluctant to prescribe insulin to their patients. The aim of the present study was to clarify any differences in, as well as any problems associated with, insulin therapy in patients wi...

INTRODUCTION Hospital patients recovering from critical illness on general floors often receive insulin therapy based on protocols designed for patients admitted directly to general floors. The objective of this study is to compare glycemic control and insulin dosing in patients recovering from critical illness and those without prior critical illness. METHODS Medical record review of blood g...

Background: Treatment for postprandial glycemia using rapid-acting insulin analogues sometimes resulted in preprandial hypoglycemia or weight gain. Objective: This study evaluated the efficacy and safety of switching bolus insulin from insulin lispro (Lis) to insulin glulisine (Glu) in patients with inadequately controlled diabetes on intensive insulin therapy with Lis and glargine (Gla). Metho...

Design. Randomized, controlled trial at a single academic teaching hospital. subjects. Four hundred patients undergoing on-pump cardiac surgery. Mean age was 63 years, 69% were men, 96% were white, and 20% had a history of diabetes. Methods. Patients were assigned randomly to receive either conventional intraoperative glucose control (treatment for blood glucose > 200 mg/dl) or intensive contro...

INTRODUCTION Cardiovascular disease (CVD) is a common and serious complication of type 2 diabetes mellitus (T2DM) often linked to the increased morbidity and mortality associated with T2DM. Monitoring and treating risk factors for CVD are important elements of diabetes management. This review aims to examine CV risk in people with relatively early and mild diabetes who are at substantial risk o...

The issue of tight glucose control with intensive insulin therapy in critically ill patients remains controversial. Although compelling evidence supports this strategy in postoperative patients who have undergone cardiac surgery, the use of tight glucose control has been challenged in other situations, including in medical critically ill patients and in those who have undergone non-cardiac surg...

PURPOSE Current forms of insulin delivery used in the treatment of diabetes mellitus (diabetes) include syringes, pens, and insulin pumps. Technical advantages of insulin pump therapy, or continuous subcutaneous insulin delivery (CSII), include precise and flexible insulin dosing. In the context of intensive diabetes management, insulin pumps can facilitate improved long-term glycemic control a...

For people living with type 1 diabetes, the Holy Grail of a closed-loop artificial system, combining glucose measurement and insulin delivery without requiring input from the individual with the condition, remains elusive.1 At present, the optimum approach appears to be a combination of insulin pump therapy and real-time continuous glucose monitoring.2 However, despite patient acceptance of thi...