نتایج جستجو برای: hydrolases

تعداد نتایج: 15143  

Journal: :Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 1974

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2011

Journal: :Frontiers in Cellular and Infection Microbiology 2020

Journal: :Current Biology 2001
Sean Munro

Correspondence The MRH domain suggests a shared ancestry for the mannose 6-phosphate receptors and other N-glycan-recognising proteins Sean Munro N-linked glycans are a prominent feature of many cell surface glycoproteins, but they are also involved in a number of important intracellular processes, including protein folding and degradation in the endoplasmic reticulum (ER), and sorting of prote...

Journal: :The Journal of biological chemistry 2002
Mindan K Sfakianos Landon Wilson Michael Sakalian Charles N Falany Stephen Barnes

Human bile acid-CoA:amino acid N-acyltransferase (hBAT), an enzyme catalyzing the conjugation of bile acids with the amino acids glycine or taurine has significant sequence homology with dienelactone hydrolases and other alpha/beta hydrolases. These enzymes have a conserved catalytic triad that maps onto the mammalian BATs at residues Cys-235, Asp-328, and His-362 of the human sequence, albeit ...

2016
Perrin Baker Preston J Hill Brendan D Snarr Noor Alnabelseya Matthew J Pestrak Mark J Lee Laura K Jennings John Tam Roman A Melnyk Matthew R Parsek Donald C Sheppard Daniel J Wozniak P Lynne Howell

Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key component of biofilm formation in the opportunistic human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharides Pel and Psl, which are involved in the formation and maintenance of the structural biofilm scaffold and protection against antimicrobi...

2015
Meng Wang Guo-Li Lai Yong Nie Shuang Geng Liming Liu Baoli Zhu Zhongping Shi Xiao-Lei Wu

In biofuel production from lignocellulose, low thermostability and product inhibition strongly restrict the enzyme activities and production process. Application of multiple thermostable glycoside hydrolases, forming an enzyme "cocktail", can result in a synergistic action and therefore improve production efficiency and reduce operational costs. Therefore, increasing enzyme thermostabilities an...

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