نتایج جستجو برای: hsct
تعداد نتایج: 3502 فیلتر نتایج به سال:
AIM To retrospectively assess if the modified lung function score (LFS) and/or its components, forced expiratory volume within the first second (FEV1) and diffusion capacity for carbon monoxide corrected for hemoglobin level (cDLCO), predict overall survival (OS) and chronic graft-vs-host-disease (cGvHD). METHODS We evaluated 241 patients receiving allogeneic hematopoietic stem cell transplan...
After allogeneic hematopoietic stem cell transplantation (HSCT), recovery of humoral immunity is essential to protect from life-threatening infections. However, monitoring the humoral immune system after transplantation with standard techniques in the clinical routine is imprecise. Here, we performed sequencing of mononuclear bone marrow cells to characterize the VH1-repertoire of switched B ce...
background: it is suggested that ha-1 mismatching among hematopoietic stem cell transplanted recipients-donors is associated with acute graft-versus-host disease (agvhd). so the aim of this study was to evaluate ha-1 frequency and examine the correlation between ha-1 disparity and gvhd patients who received transplantation from a hla-identical sibling. samples and methods: the dna was extracted...
Abstract Background Varicella-zoster virus (VZV) infection is known to occur in 13-55% of patients within the first year after hematopoietic stem cell transplant (HSCT). The dynamics recovery VZV-specific T cell- mediated immunity (CMI) and its role for prevention control VZV reactivation are rarely reported pediatric allogenic HSCT recipients. Methods From April 2019 February 2020, subjects ag...
IMPORTANCE Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease. OBJECTIVE To evaluate the effect of autologous HSCT on refractory Crohn disease. DESIGN, SETTING, AND PARTICIPANTS Parallel-group randomized clinical trial conducted in 11 European transplant units from July 2007 to September 2011, with follow-up through Ma...
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. What should we consider in mixed chimerism after hemato-poietic stem cell transplanta-tion? TO THE EDITOR: Mixed chimerism (MC) was initially thought to indicate impending relapse; however, it has become clear that it is an important parameter for estimating...
Efficient reconstitution of the pool of peripheral T cells after hemopoietic stem cell transplantation (HSCT) is dependent on normal thymic function. However, the development of graft-vs-host disease (GVHD) in the context of allogeneic HSCT is associated with injurious effects on thymocyte development. In this study, we examined in models of syngeneic and allogeneic murine HSCT whether actual p...
Abstract Background Hematopoietic stem cell transplant (HSCT) has been increasingly used in the last few decades, with improved success offering a cure. CNS complications are an important contributor to morbidity and mortality HSCT patients. The aim of study was evaluate role imaging detection assessment CNSC (central nervous system complications) after pediatric oncology included consecutive p...
The article analyzes the potential of using impulse oscillometry in diagnosis respiratory disorders children with oncological and hematological diseases after allogeneic hematopoietic stem cell transplantation (HSCT). study was approved by Independent Ethics Committee Scientific Council Dmitry Rogachev National Medical Research Center Pediatric Hematology, Oncology Immunology Ministry Healthcar...
Objectives: Identical hematopoietic stem cell transplantation (haplo-HSCT) is associated with a higher risk of graft rejection when compared to matched sibling donor transplantations. Methods: The study included 34 patients who were treated novel regimen combining basiliximab, Anti-thymocyte globulin (ATG) and conventional immunosuppressive in the recipients haplo-HSCT. Results: cumulative inci...
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