Objectives: Eβ-thalassemia, the most serious form of HbE syndromes, may develop pre-diabetes (PD) and diabetes mellitus (DM), together constituting abnormal glucose homeostasis (AGH) as an endocrinopathy. This study aims to assess AGH prevalence pathogenesis in this thalassemia subtype. Material Methods: A cross-sectional was conducted at a tertiary care hospital from February 2017 December 201...

Growing evidence supports that air pollution exposure has become a risk factor of type II diabetes mellitus through the induction insulin resistance (IR), but presented findings did not provide consistent relationship between and IR in temporal scale magnitude. Reported associated with exposure, branched-chain amino acids (BCAAs) blood might modify association IR. We took advantage an existing ...

4.3. (i) Since HomA(A (I),M) ∼= M (I) for a set I and ⊕ is exact, it is clear that HomA(A (I),−) is exact, i.e. A(I) is projective. (ii) “Only if” part: Let A(P ) = ⊕ p∈P Ap be the free A-module indexed by P and ψ : A (P ) → p be the A-homomorphism such that ψ(1p) = p. Then ψ is surjective. If P is projective, then ψ has a section, i.e. an A-homomorphism φ : P → A(P ) such that ψ ◦ φ = idP . Th...

intake of socially undesirable sucrosecontaining foods. These assumptions would never be reliable. Thus, we recommended caution when interpretation of results from this part of our study. The last point raised by Buyken and Liese was that alcohol intake may predict glycemic index of the diet and hence affect the estimates of glycemic index and glycemic load. The reported associations are relati...

The aim of the study was to test the performance of a new definition of metabolic syndrome (MetS), which better describes metabolic dysfunction in children. Methods. 15,794 youths aged 6-18 years participated. Mean z-score for CVD risk factors was calculated. Sensitivity analyses were performed to evaluate which parameters best described the metabolic dysfunction by analysing the score against ...

OBJECTIVE Insulin resistance (IR) and associated metabolic abnormalities are increasingly being reported in the adolescent population. Cut-off value of homeostasis model of assessment IR (HOMA-IR) as an indicator of metabolic syndrome (MS) in adolescents has not been established. This study aimed to investigate IR by HOMA-IR in urban Indian adolescents and to establish cut-off values of HOMA-IR...

BACKGROUND Insulin-resistance is associated with cardiovascular disease but it is not used as a marker for disease in clinical practice. AIMS To study the association between the homeostatic model assessment (HOMA-IR) and triglyceride/HDLc ratio (TG/HDLc) with the presence of coronary artery disease in patients submitted to cardiac catheterization. METHODS In a cross-sectional study, 131 pa...

OBJECTIVE To assess the individual variability of HOMA and QUICKI indexes for the assessment of insulin resistance, using three fasting blood samples obtained within 30 minutes. RESEARCH METHODS & PROCEDURES Data from 80 participants aged 41.5 ± 15 years (26 females), who underwent an oral glucose tolerance test to calculate Matsuda index, were used. Every participant had three fasting blood ...

OBJECTIVE To determine the association of insulin sensitivity and pancreatic beta-cell function parameters assessed by the homeostasis model assessment (HOMA) and glycemic control, and their potential utilization in the clinical care of patients with type 2 diabetes mellitus. MATERIAL AND METHOD The HOMA indices were assessed in 204 (62 males, 142 females) type 2 diabetic outpatients aged 60....