1. The aim of this experiment was to study the interactive effect of rearing temperature and dietary supplementation of arginine (Arg) or guanidinoacetic acid (GAA) on performance, gut morphology and ascites indices in broiler chickens raised under the same condition in the first 2 weeks and then reared under normal (23-26°C) or subnormal (17°C) ambient temperatures for the next 3 weeks. 2. Thi...

Friedreich's ataxia (FRDA) is caused by large GAA expansions in intron 1 of the frataxin gene (FXN), which lead to reduced FXN expression through a mechanism not fully understood. Understanding such mechanism is essential for the identification of novel therapies for FRDA and this can be accelerated by the development of cell models which recapitulate the genomic context of the FXN locus and al...

Studies were conducted to assess glacial acetic acid (GAA) with various host plant volatiles (HPVs) and the sex pheromone, (E,E)-8, 10-dodecadien-1-ol, of codling moth, Cydia pomonella (L), as lures in traps for tortricid pests that often co-occur in tree fruits in the western United States. In addition to codling moth, field trapping studies were conducted with oriental fruit moth, Grapholita ...

Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by a GAA repeat expansion mutation within intron 1 of the FXN gene, resulting in reduced levels of frataxin protein. We have previously reported the generation of human FXN yeast artificial chromosome (YAC) transgenic FRDA mouse models containing 90-190 GAA repeats, but the presence of multiple GAA repeats wi...

Large strain-energy arising from lattice mismatch allows one-dimensional heteroepitaxial growth of InxGa1−xAs on silicon substrates without any catalyst or pattern assistance. In this paper, we show that in contrast to nanowires (NWs) grown by metal-catalyzed vapor−liquid− solid mechanism, strain-induced InxGa1−xAs NWs have several unique morphological features including no tapering, slight ben...

In this paper, the innovations in device design of gate-all-around (GAA) nanosheet FET are reviewed. These span enablement multiple threshold voltages and bottom dielectric isolation addition to impact channel geometry on overall performance. Current scaling challenges for GAA FETs reviewed discussed. Finally, an analysis future required continue technologies is

With an amorphous silicon (a-Si:H)/crystalline silicon (c-Si) heterojunction structure, the heterojunction with intrinsic thin-layer (HIT) solar cell has become one of the most promising technologies for c-Si based solar cells. By replacing a-Si:H thin films with appropriate compound semiconductors, we propose novel heterojunction structures which allow c-Si heterojunction solar cells to posses...

Atmospheric Chemistry and Physics Discussions This discussion paper is/has been under review for the journal Atmospheric Chemistry and Physics (ACP). Please refer to the corresponding final paper in ACP if available. Abstract To identify the relative contribution of local versus regional sources of particulate matter (PM) in the Greater Athens Area (GAA), simultaneous mass and chemical composit...

background: expansion of gaa trinucleotide repeats is the molecular basis of friedreich’s ataxia (frda). precise detection of the gaa expansion repeat in frataxin gene has always been a challenge. different molecular methods have been suggested for detection of gaa expansion, including; short-pcr, long-pcr, triplet repeat primed-pcr (tp-pcr) and southern blotting. the aim of study was to evalua...

We describe a quantum mechanics/molecular mechanics investigation of the guanidinoacetate methyltransferase catalyzed reaction, which shows that proton transfer from guanidinoacetate (GAA) to Asp-134 and methyl transfer from S-adenosyl-L-methionine (AdoMet) to GAA are concerted. By self-consistent-charge density functional tight binding/molecular mechanics, the bond lengths in the concerted mec...