conclusions ehp was able to both reduce ldl-ch and to significantly decrease markers of oxidative stress and lipid peroxidation induced by hyperlipidemia. therefore, this herb, as a new pharmacological component, could be used to reduce certain blood lipids, lipid peroxidation, and aminotransferase markers. materials and methods thirty-two male rats weighting 200 ± 10 g were randomly divided in...

Hepatotoxicity secondary to carbamazepine is a serious condition which can be fatal. However, other concomitant medications or environmental factors may be the offending agents. In this case report, hepatotoxicity secondary to organic solvents and paints is described.

The hepatoprotective properties of Alchornea cordifolia, a medicinal plant was studied in hepatotoxicity induced animal model with high dose paracetamol or carbon tetrachloride. Knowing that antituberculosis drugs also represent risk factor for hepatotoxicity, could A. cordifolia play key role to limit their hepatotoxicity? objective this study assess the histological changes rat livers and evo...

hydroxypyridinone iron chelators are currently the main candidates for development of orally active iron chelating alternatives to desferrioxamine (dfo). in the present study, the relative efficacy and liver toxicity of a bidentate chelator, 2-methyl-3-hydroxypyridin-4-one (mhpo), was studied in iron overloaded rats and compared with those of dfo. for iron overloading, rats received i.p. inject...

objective: studies reported conflicting results’ regarding the status of depression and glycemic control in patients with type ii diabetes(t2dm), therefore, this study was performed to determine the relationship between depression and glycemic control in t2dm patients. materials and methods: this cross-sectional study was performed on 150 t2dm patients referred to yazd diabetes research center,...

background: coronary artery diseases are one of the most important issues in health and social problems. one of the amendable risk factors in development of these diseases is high cholesterol which can be modified through correction of lifestyle (diet change, playing sports, and usage of lipid‑lowering drugs). patients’ compliance to therapeutic programs is the most important element to achieve...

background: we are aware of limited data about the effects of purslane on diabetes. earlier studies have mostly indicated the beneficial effects in animal models. this study aimed to evaluate the effect of purslane seeds on glycemic status and lipid profiles of type 2 diabetic patients. methods: this cross-over randomized controlled clinical trial was conducted on 48 diabetic patients. particip...

use of medicinal plants for attenuation of hyperglycemia and restoration of lipids disorder to normal level is clinically very important. the aim of present study was to evaluate the effects of berberis integerrima bge. fruit aqueous extract (bifae) on blood glucose and lipid profile in streptozotocin (stz) - induced diabetic rats. the stz-induced diabetic rat were treated by fruit aqueous extr...

background: hyperlipidemia is one of the most important factors in progression of coronary heart diseases, because of the importance of lipid control for preventing heart disease; this study has done to explore the relation between health beliefs and medications adherences in patients with hyperlipidemia. methods: this correlation study has done in 82 patients with hyperlipidemia. for obtain in...

BACKGROUND Although hyperlipidemia is known as a risk factor of stroke, its effects on the outcome are unknown. The aim of the study is to clarify the influences of hyperlipidemia on the stroke early outcome by estimating odds ratio (OR) for sequelae requiring care and hazard ratio (HR) for death. METHODS A total of 12617 stroke patients registered in the Kyoto Stroke Registry with informatio...