نتایج جستجو برای: hepatotoxic
تعداد نتایج: 1645 فیلتر نتایج به سال:
The aim of this work was to evaluate the nutritional and hepatotoxic potential leaf T. danielli. Freshly harvested leaves danielli dried at room temperature, ground fine powder. 500 g powdered plant sample soaked in 2 litres 70% methanol for 72 hrs. resulting extract filtered filtrate concentrated. Twenty adult male albino rats were divided into 4 groups 5 per group. · Group I: Normal control f...
Blooms of microcystin-producing cyanobacteria are a problem worldwide. Microcystin is a liver hepatotoxin commonly found in bodies of water and is produced mainly by the genus Microcystis. The aim of the present study was to develop and assess a competitive PCR method for the quantification of toxic and non-toxic Microcystis cells using the cpcBA and mcyB genes, which are respectively involved ...
Cisplatin (CP) is a widly used anticancer drug against abroad spectrum of malignance, but at high dose, it can produce undesirable effects such as hepatotoxicity. The aim of this study was to investigate the possible protective effect of erdosteine (Erd) against CP-induced biochemical, histopathological changes and hepatotoxicity associated with oxidative stress and inflammatory changes in male...
A series of acetaminophen (APAP) analogs, 2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)-N-(4-hydroxyphenyl)alkanecarboxamides, bearing a heterocyclic moiety linked to the p-acylaminophenol fragment, were prepared in a general project to develop APAP analogs with modulated pharmacokinetic profiles. Unexpectedly, the products described maintained the in vivo analgesic profile, while the chara...
PURPOSE Long-term ketogenic diet (KD) treatment has been shown to induce liver steatosis and gallstone formation in some in vivo and clinical studies. The aim of this retrospective study was to evaluate the hepatic side effects of KD in epileptic children. METHOD A total of 141 patients (mean age: 7.1±4.1years [2-18 years], 45.4% girls), receiving KD at least one year for intractable epilepsy...
In the current research, rats will be given RIF+INH (hepatotoxic), and hydoethanol (HEESV) extract of leaves Sida veronicaefolia tested to see how well it protects rats' livers from damage caused by RIF+INH. Liver function tests serum profiles were used provide an estimate hepatoprotective effects HEESV at a dose 500 mg/kg. According findings, extracts not only strong impact lowering blood leve...
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