Sudden death is very common in heart failure, and its occurrence is considerably underestimated. Data from the second cardiac insuYciency bisoprolol study (CIBIS II) and the metoprolol CR/XL randomised intervention trial in heart failure (MERIT-HF) on total mortality, total cardiovascular mortality, sudden death, and heart failure, show clearly that sudden death is extremely common in patients ...

Heart failure with improved ejection fraction (HFiEF) is a novel heart (HF) subgroup. There are sparse data on using NT-proBNP, growth differentiation factor 15 (GDF15) and global longitudinal strain (GLS) to characterize prognosticate HFiEF patients.

AIMS To compare quality of life (QoL) in heart failure (HF) patients with preserved ejection fraction (HF-PEF) and HF patients with reduced ejection fraction (HF-REF) in a well-defined HF population. METHODS AND RESULTS Patients with HF-PEF [left ventricular ejection fraction (LVEF) ≥40%] were matched by age and gender to patients with HF-REF (LVEF <40%). In the current study, we only include...

AIMS Socioeconomic position has been linked to incident heart failure (HF), but the underlying mechanisms are unclear. We examined the association of socioeconomic measures with incident HF in older adults and examined possible underlying pathways. METHODS AND RESULTS A socially representative cohort of men aged 60-79 years in 1998-2000 from 24 British towns was followed-up for 10 years for i...

Abstract Background The association between heart failure (HF) patients and the incidence of cancer is not well understood, with conflicting results to date. Objective aim this meta-analysis was evaluate whether HF have a higher risk developing cancer. Material Methods We performed systematic literature search using PubMed, Embase, Scopus for relevant articles from inception until 10th December...

Heart failure (HF) is a major cause of morbidity and mortality in high income countries. Shortage of population based HF studies from Low and Middle Income countries (LMIC) make global prevalence estimates difficult. In this editorial we discuss the possibility of generating HF data in LMICs by initiating HF surveillance systems integrated into the existing health surveillance system.

Heart failure (HF) is a complex clinical syndrome resulting from diverse primary and secondary causes and shared pathways of disease progression, correlating with substantial mortality, morbidity, and cost. HF in children is most commonly attributable to coexistent congenital heart disease, with different risks depending on the specific type of malformation. Current management and therapy for H...

Heart Failure (HF) is a complicated, fatal medical condition that poses severe threat to human life. It complex ailment can lead death and associated with high healthcare costs, significant morbidity mortality rates, reduction in functional capacity quality of Recent data analysis reveals approximately 64million people worldwide are affected by HF.1 Patients HFrEF benefit from cardiac contracti...

The new ESC heart failure guidelines, an update of the 2008 version, was released at the ESC Heart Failure Congress in Belgrade this weekend. This is the first time the guidelines have been presented at the Heart Failure Congress as opposed to at the annual European Society of Cardiology (ESC) Congress. Major updates are in the provision of new algorithms for the diagnosis of patients with susp...

BACKGROUND Heart failure (HF) inpatient mortality prediction models can help clinicians make treatment decisions and researchers conduct observational studies; however, published models have not been validated in external populations. METHODS AND RESULTS We compared the performance of 7 models that predict inpatient mortality in patients hospitalized with acute decompensated heart failure: 4 ...