نتایج جستجو برای: haplotype analysis
تعداد نتایج: 2832840 فیلتر نتایج به سال:
conclusions the widespread distribution of l. major parasites in human suggests not only t. indica was the main reservoir but also other rodents and mammalian hosts might be the reservoir hosts of zcl in the region. molecular and phylogenetic analyses confirmed the strength of haplotype variation maintaining the circulation of leishmania species in their reservoir hosts. results leishmania majo...
The genetic diversity of five natural populations milkfish (Chanos chanos) collected in Nghe An, Quang Binh, Binh Dinh, Phu Yen, Khanh Hoa provinces Vietnam was examined using COI gene sequence analysis. Twelve haplotypes were noted from a total 50 sequences along with 12 variable sites and 6 parsimony informative sites. population had the highest haplotype (0.889 ± 0.060) nucleotide diversitie...
Association-based linkage disequilibrium (LD) mapping is an increasingly important tool for localizing genes that show potential influence on human aging and longevity. As haplotypes contain more LD information than single markers, a haplotype-based LD approach can have increased power in detecting associations as well as increased robustness in statistical testing. In this paper, we develop a ...
Gaucher's disease (GD) is the most frequent lysosomal storage disorder resulting from a deficiency of the enzyme glucocerebrosidase (GBA) which causes the accumulation of glucocerebroside. More than 500 mutations have been reported on the GBA gene so far. In this study, we aimed to investigate more on the genotype of less known mutations through haplotype analysis to explain their disease-causi...
BACKGROUND Interleukin 6 (IL-6) is a key proinflammatory cytokine in the systemic inflammatory response syndrome (SIRS). A G-->C polymorphism at position -174 of the IL-6 gene is associated with an adverse outcome in a number of inflammatory diseases, although its association with sepsis as an outcome remains unclear. We tested the hypothesis that specific haplotype clades of IL-6 may be associ...
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