BACKGROUND AND AIMS 13C-Ketoisocaproic Acid Breath Test (13C-Kica-BT) has been proposed to assess mitochondrial function. Aim of this study is to evaluate whether gender affects mithocondrial oxidation by means of 13C-Kica-BT in healthy subjects in basal conditions and after an acute oxidative stress induced by ethanol. METHODOLOGY 50 healthy volunteers were given 1 mg/kg of 13C-Kica together...

The clinical manifestations of non-erosive gastroesophageal reflux disease (NERD) are multiple and heterogeneous, and differ according to age and individual susceptibility. Weakly acidic reflux and the presence of gas in the refluxate could be relevant in the pathogenesis of symptoms. We present the case of a 3-year and 5-month-old child who came to the hospital with recurrent paroxysmal manife...

It has been proven that certain biomarkers in people's breath have a relationship with diseases and blood glucose levels (BGLs). As a result, it is possible to detect diseases and predict BGLs by analysis of breath samples captured by e-noses. In this paper, a novel optimized medical e-nose system specified for disease diagnosis and BGL prediction is proposed. A large-scale breath dataset has b...

RESPIRATORY GAS EXCHANGE PHYSIOLOGY began with the description of oxygen and carbon dioxide exchange in a one-compartment lung, followed decades later by investigation of the effects of heterogeneity. Those studies were followed by experiments utilizing multiple intravenously infused inert gases of varying blood solubility to further investigate ventilation-perfusion heterogeneity. More recentl...

Sucrose breath hydrogen tests were performed on 7 children with proved sucrase isomaltase deficiency. All children had raised breath hydrogen excretion. The amount of hydrogen produced and symptoms experienced increased with increasing sucrose loads. The sucrose breath hydrogen test appears to be a reliable indicator of sucrose malabsorption in sucrase isomaltase deficiency.

TO THE EDITOR: With great interest we have been following the discussion about our study published in Journal of Neurogastroenterology and Motility. 1 We highly estimate the recent constructive comments expressed by the authors Erdogan and colleagues 2 and would like to make some conclusive remarks. We fully agree with the authors that all patients with irritable bowel syndrome (IBS)-like sympt...

Background: The prevalence of Helicobacter pylori (H. pylori) infection in patients with rosacea is reported from 50 to 90 percent, which suggests the possibility of the role of this organism in pathogenesis of rosacea. Objectives: Evaluation of relationship between H. pylori infection and rosacea. Patients and Methods: In this case-control study, 30 patients referred to skin clinics of B...

Objective: Helicobacter pylori (H. pylori) is the most common pathogenic bacteria in the stomach. The aim of the current study was to explore the effect of oral garlic administration on bacterial urease activity inside the stomach and its contribution to the treatment of H. pylori infection.   Materials and Methods: In this clinical trial, 15 patients were studied quantitatively with Urease Bre...