BACKGROUND & OBJECTIVES In recent years, health-related quality of life (QOL) has been regarded as the most important dimension of outcome in schizophrenia. Recent research has shown that atypical antipsychotics improve QOL in patients with schizophrenia. Importance of electroconvulsive therapy (ECT) has been demonstrated in restoring function and health related quality of life in depressed pat...

OBJECTIVE A prospective study was conducted in order to establish whether AS patients, who are defined as non-responders after 3 months of anti-TNF therapy, show improvement on performance-based tests of physical functioning. METHODS At baseline and 3 months after the start of anti-TNF therapy, AS patients completed seven performance-based tests of physical functioning, questionnaires on self...

background : there is an increasing incidence of colorectal cancer in malaysia. the aim of this study is to evaluate sociodemographic data, knowledge, awareness, practice level, and quality of life in colorectal cancer patients. methods : a cross-sectional study was conducted from december 2011 to june 2012 that involved 105 patients diagnosed with colorectal cancer at four chosen tertiary gove...

OBJECTIVES To evaluate the clinical effectiveness of group art therapy for people with schizophrenia and to test whether any benefits exceed those of an active control treatment. DESIGN Three arm, rater blinded, pragmatic, randomised controlled trial. SETTING Secondary care services across 15 sites in the United Kingdom. PARTICIPANTS 417 people aged 18 or over, who had a diagnosis of schi...

Objectives To evaluate the clinical effectiveness of group art therapy for people with schizophrenia and to test whether any benefits exceed those of an active control treatment. Design Three arm, rater blinded, pragmatic, randomised controlled trial. Setting Secondary care services across 15 sites in the United Kingdom. Participants 417 people aged 18 or over, who had a diagnosis of schizophre...

OBJECTIVES The aim of the project was to assess changes of occupational and relational functioning within 2 years period of ambulatory treatment of persons suffering from different mental disorders. MATERIAL AND METHOD Outpatients (n = 184) at the age of 18-54 from five diagnostic groups - according to ICD-10: psychotic disorders (F2), affective disorders (F3), anxiety disorders (F4), eating ...

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of 30 mL Cerebrolysin is a safe and effective drug for improving global and cognitive function in patients with Alzheimer’s Disease aged 50 years and older with no significant comorbidities. STUDY DESIGN: Systematic review of three randomized controlled trials published between 2001-2006, all English la...

CONTEXT Low-functioning patients with chronic schizophrenia have high direct treatment costs and indirect costs incurred due to lost employment and productivity and have a low quality of life; antipsychotic medications and psychosocial interventions have shown limited efficacy to promote improved functional outcomes. OBJECTIVE To determine the efficacy of an 18-month recovery-oriented cogniti...