نتایج جستجو برای: fatty acid elongase gene

تعداد نتایج: 1796572  

Introduction: Omentin, an adipokine, with anti-inflammatory effects reduces insulin resistance, and can hence, play an important role in prevention of cardiovascular disease and diabetes. The present study aimed to investigate the association of plasma and dietary fatty acids with gene expression of omentin in visceral and subcutaneous adipose tissues. Materials and Methods: Visceral and subcut...

2001
Michael W. Lassner Kathryn Lardizabal James G. Metz

Jojoba [Simmondsia chinensis, Simmondsiaceae, (Link) Schnieder], a native of deserts of the American Southwest, is unusual and perhaps unique amongst higher plants in that its seed storage lipids are liquid waxes rather than triglycerides. These waxes are esters of long chain (mostly; C20, C22, and C24), monounsaturated, fatty acids and alcohols. The waxes are produced in developing embryos dur...

J. Fayazi K. Taghizadeh, M. Bujarpoor M.T. Beigi Nasiri

Stearoyl-CoA desaturase (SCD) is a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids (MUFA). A number of studies support the hypothesis that SCD gene regulation and polymorphism may affect fatty acid composition and fat quality in meat and milk. Single nucleotide polymorphisms in the coding region of the bovine stearoyl-CoA desaturase gene have been predicted to result in ...

2016
Anne Marie Minihane

At a population level, cardioprotective and cognitive actions of the fish oil (FO) derived long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been extensively demonstrated. In addition to dietary intake, which is limited for many individuals, EPA and DHA status is dependent on the efficiency of their biosynthesis from α-lino...

2013
Fernando Norambuena Michael Lewis Noor Khalidah Abdul Hamid Karen Hermon John A. Donald Giovanni M. Turchini

Teleost fish, as with all vertebrates, are capable of synthesizing cholesterol and as such have no dietary requirement for it. Thus, limited research has addressed the potential effects of dietary cholesterol in fish, even if fish meal and fish oil are increasingly replaced by vegetable alternatives in modern aquafeeds, resulting in progressively reduced dietary cholesterol content. The objecti...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Peter Barabas Aihua Liu Wei Xing Ching-Kang Chen Zongzhong Tong Carl B Watt Bryan W Jones Paul S Bernstein David Križaj

Stargardt type 3 (STGD3) disease is a juvenile macular dystrophy caused by mutations in the ELOVL4 (Elongation of very long chain fatty acids 4) gene. Its protein product, ELOVL4, is an elongase required for the biosynthesis of very long-chain polyunsaturated fatty acids (VLC-PUFAs). It is unclear whether photoreceptor degeneration in STGD3 is caused by loss of VLC-PUFAs or by mutated ELOVL4 pr...

زوار رضا, جواد , صالحی پور, مسعود, منصوری, رضا, نهنگی, حسین,

Introduction: Defect in the cholesterol homeostasis in macrophage as well as converting them to foam cells is one of the most important factors in the initiation and progression of atherosclerosis. Many genes and transcription factors like Peroxisome Proliferators Activated Receptors are involved in cholesterol homeostasis in these cells. N-3 fatty acids are one of the most important factors re...

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