The emergence of Escherichia coli resistant to extended-spectrum cephalosporins (ESCs) is of concern as ESC is often used to treat infections by Gram-negative bacteria. One-hundred and ten E. coli strains isolated in 2009-2010 from children warded in a Malaysian tertiary hospital were analyzed for their antibiograms, carriage of extended-spectrum beta-lactamase (ESBL) and AmpC genes, possible i...

Abstract Multidrug resistance due to the production of extended-spectrum beta-lactamases (ESBLs) is a major problem in human as well veterinary medicine. These strains appear animal and microbiomes can be source infection both healthcare, accordance with One Health theorem. In this study we examined prevalence ESBL-producing bacteria food-producing animals. We collected 100 porcine 114 poultry ...

Abstract Background ESBLs hydrolyze the beta-lactam ring of antibiotics and are not affected by 1st, 2nd, 3rd, 4th generation antibiotics. There over 400 ESBL enzymes that have already been investigated globally present in Enterobacteriaceae species such as Escherichia coli , Klebsiella pneumoniae oxytoca strains. Prevalence is slowly increased, from 10 to 40% E. K. pneumonia Microorganisms pro...

OBJECTIVE To describe the epidemiology of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (ESBL-EC) and Klebsiella pneumoniae (ESBL-KP) infections DESIGN Retrospective cohort SETTING Inpatient care at community hospitals PATIENTS All patients with ESBL-EC or ESBL-KP infections METHODS ESBL-EC and ESBL-KP infections from 26 community hospitals were prospectively entered into a ce...

BACKGROUND AND OBJECTIVES Resistance to a wide variety of common antimicrobials has made the proliferation of Extended spectrum β-lactmase (ESBL) producing strains a serious global health concern that has complicated treatment strategies. The high proportion of ESBL producers among the Enterobacteriaceae and the complex molecular epidemiology with diverse types of ESBL genes are alarming. This ...

BACKGROUND Ventilator Associated Pneumonia (VAP) is one of the common nosocomial infections associated with high morbidity due to multidrug resistant pathogens. Rapid spread of resistance to broad spectrum beta-lactams in pathogenic strains causes antibiotics ineffectiveness and increased severity of illness. The CTX-M is the most dominant Extended Spectrum β Lactamase (ESBL) among Enterobacter...

Corresponding Author: Viera Lovayová Department of Public Health and Hygiene, Faculty of Medicine, University of P.J. Safarik in Košice, Trieda SNP 1, 040 11 Košice, Slovakia Phone: +421915932031 Email: [email protected] Abstract: The beta-lactamases with extended spectrum of activity (ESBL) are medically one of the most important group of enzymes. The presented study provides identificati...

Background Due to increasing colistin usage, the dissemination of the colistin-resistant gene mcr-1 has been increasingly investigated. The aim of this study was to determine whether a traveler on a short-term international trip to a developing country could bring mcr-1 back to their home country. Materials and methods Thirty-four travel events from Japan to Vietnam encompassing 19 travelers ...

This study was conducted to reveal the phylogenetic background, to detect the genes encoding TEM, SHV and CTX-M-15 extended-spectrum β-lactamases (ESBL), and to analyze their distribution in phylo-groups of 150 Escherichia coli isolates from broiler chickens in Ahvaz (Southwest of Iran). Seventy- five cloacal swabs from healthy birds (fecal isolates), and 75 heart blood samples from bi...