نتایج جستجو برای: enamel matrix protein

تعداد نتایج: 1550209  

Journal: :Scientific Reports 2016

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Journal: :Neural Processing Letters 2013

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Journal: :Protein expression and purification 2009
B Shay Y Gruenbaum-Cohen A S Tucker A L Taylor E Rosenfeld A Haze L Dafni Y Leiser E Fermon T Danieli A Blumenfeld D Deutsch

Tuftelin is an acidic protein expressed at very early stages of mouse odontogenesis. It was suggested to play a role during epithelial-mesenchymal interactions, and later, when enamel formation commences, to be involved in enamel mineralization. Tuftelin was also detected in several normal soft tissues of different origins and some of their corresponding cancerous tissues. Tuftelin is expressed...

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2017
Rozita Jalali Johannes C. Lodder Behrouz Zandieh-Doulabi Dimitra Micha James E. Melvin Marcelo A. Catalan Huibert D. Mansvelder Pamela DenBesten Antonius Bronckers

Na+:K+:2Cl- cotransporters (NKCCs) belong to the SLC12A family of cation-coupled Cl- transporters. We investigated whether enamel-producing mouse ameloblasts express NKCCs. Transcripts for Nkcc1 were identified in the mouse dental epithelium by RT-qPCR and NKCC1 protein was immunolocalized in outer enamel epithelium and in the papillary layer but not the ameloblast layer. In incisors of Nkcc1-n...

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Journal: :Journal of dental research 2003
T Nagano S Oida H Ando K Gomi T Arai M Fukae

Amelogenin, enamelin, sheathlin (ameloblastin/ amelin), enamelysin (MMP-20), and KLK4 (EMSP-1) are the major structural proteins and proteinases in developing tooth enamel. Recently, odontoblasts were reported to express amelogenin, the most abundant enamel protein. In this study, we hypothesized that odontoblasts express all enamel proteins and proteases, and we measured their relative mRNA le...

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Journal: :THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN 1996

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Journal: :Japanese Journal of Oral Biology 1982

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Journal: :International Journal of Oral Science 2012

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Journal: :Journal of biomedical optics 2016
Khalifa Al-Azri Lucia N Melita Adam P Strange Frederic Festy Maisoon Al-Jawad Richard Cook Susan Parekh Laurent Bozec

Molar incisor hypomineralization (MIH) affects the permanent incisors and molars, whose undermineralized matrix is evidenced by lesions ranging from white to yellow/brown opacities to crumbling enamel lesions incapable of withstanding normal occlusal forces and function. Diagnosing the condition involves clinical and radiographic examination of these teeth, with known limitations in determining...

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Journal: :Human molecular genetics 2005
Hiroshi Masuya Kunihiko Shimizu Hideki Sezutsu Yoshiyuki Sakuraba Junko Nagano Aya Shimizu Naomi Fujimoto Akiko Kawai Ikuo Miura Hideki Kaneda Kimio Kobayashi Junko Ishijima Takahide Maeda Yoichi Gondo Tetsuo Noda Shigeharu Wakana Toshihiko Shiroishi

Amelogenesis imperfecta (AI) is a group of commonly inherited defects of dental enamel formation, which exhibits marked genetic and clinical heterogeneity. The genetic basis of this heterogeneity is still poorly understood. Enamelin, the affected gene product in one form of AI (AIH2), is an extracellular matrix protein that is one of the components of enamel. We isolated three ENU-induced domin...

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