نتایج جستجو برای: duplexes

تعداد نتایج: 2374  

Journal: :Journal of the American Chemical Society 2017

Journal: :Journal of Investigative Dermatology 2023

The study was aim to examine the role and mechanism of Proprotein convertase subtilisin/kexin type 9 (PCSK9) in ultraviolet B (UVB)-induced skin damage. PCSK9 is an enzyme that promotes degradation low-density lipoprotein receptors. It involved hyperlipidemia as well other diseases, such cancer inflammation. However, detail for on lesions not clear. Thus, we aimed possible action UVB-induced A ...

Journal: :Chemical communications 2010
Kakoli Dutta Takeshi Fujimoto Mamiko Inoue Daisuke Miyoshi Naoki Sugimoto

The sequence specificity of a duplex and the cation dependent self-assembly of a G-quadruplex were combined to design rationally DNA G-quadruplex arrays connected by duplexes.

Journal: :Chemical communications 2004
Jennifer L Czlapinski Terry L Sheppard

Ni-salen-DNA conjugates, prepared by template-directed synthesis, targeted oxidative adduct formation and strand scission at deoxyguanosine sites in complementary DNA strands of Watson-Crick duplexes.

Journal: :Journal of the American Chemical Society 2005
Lilu Zhang Adam Peritz Eric Meggers

A glycol nucleic acid (GNA) with an acyclic propylene glycol phosphodiester backbone forms stable antiparallel duplexes following the Watson-Crick base pairing rules.

Journal: :Journal of the American Chemical Society 2018

Journal: :Bioconjugate chemistry 2009
Sina Berndl Nadine Herzig Péter Kele Daniel Lachmann Xiaohua Li Otto S Wolfbeis Hans-Achim Wagenknecht

The azides 1 and 2 bearing a phenoxazinium and a coumarin fluorophore, respectively, were applied in postsynthetic "click"-type bioconjugation and coupled to oligonucleotides modified with alkyne groups using two alternative approaches: (i) as a nucleotide modification at the 2'-position of uridine and (ii) as a nucleotide substitution using (S)-(-)-3-amino-1,2-propanediol as an acyclic linker ...

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