A dosimetry system using commercially available pin silicon photodiodes as the sensor is evaluated for in-phantom dose measurements in x-ray CT and other diagnostic radiology. System sensitivity measured as a function of the effective energy of x rays was between 0.37 and 0.49 V/mGy at an effective energy range between 23.5 and 72 keV. The minimum detectable organ dose with 25% uncertainty was ...

Mechanistic and epidemiologic studies provide considerable evidence for a protective association between calcium intake and incident colorectal cancer (CRC). While the relationship has not been substantiated by short-duration randomized controlled trials (RCTs) of CRC, trials do show a benefit on adenomas, a precursor to CRC. To address some of this inconsistency, we conducted dose-response met...

A simple, accurate, precise and rapid stability indicating reverse phase High performance chromatography method was used for estimation of Sitagliptin/metformin HCl ER tablets in bulk fixed-dose combination solid oral dosage form. The proposed analytical has been validated specificity, Linearity, Accuracy, Precision Robustness. achieved a Avantor, ACE C18 (Length 150 x Diameter 4.6mm Particle s...

For the first time, samples of magnesium oxide ceramics were obtained by a method based on irradiation powders with beam fast electrons. Luminescence centers associated intrinsic and impurity defects found in samples. A comparative analysis thermoluminescence (TL) curves dose dependencies TL MgO radiation thermochemical methods is carried out. The linear dependence peak at 370 K excited pulsed ...

Background and Aims: As a method for the diagnosis and management of sepsis, the serum procalcitonin assay is routinely used, especially in the emergency department (ED) and intensive care units (ICU). Procalcitonin has reasonable diagnostic accuracy for bacteremia in hospitalized patients of all age groups with suspected infection or sepsis. This study aimed to compare the Getein Biotech proca...

The majority of EPID dosimetry literature discusses response linearity and the so-called image lag and ghosting effects despite the lack of a common definition of these quantities. However, the results of these studies are generally not consistent, and it is often difficult to compare the results from different studies. We present here a detailed study of the acquisition and readout characteris...

Cancer risk assessment for TCDD and other compounds must focus on the cancer dose-response relationship and corresponding potency for the range of human doses before it can have relevance to the human exposure environment. Major differences of opinion exist over whether the dose-response curve for TCDD and other dioxin congeners is non-linear (incorporating a threshold dose region below which t...

• DDIs to Saccharomyces cerevisiae gene expression profiles is studied. Integrated analyses was performed towards the collection of obtained by multiple drugs treatments. Novel unsupervised tensor-based method for evaluating proposed. Findings demonstrate non-linear kinetics at various doses. The proposed contributes a better understanding DDIs. accurate prediction new interactions between impo...