background : hepatitis b virus (hbv) is one of the most popular causes of chronic liver diseases through the world. there are approximately 350 million individuals infected with the hbv that 15 to 20 million of them are co-infected with hdv. it is known that co-existent infection with hdv tends to accelerate the progress of chronic hbv infection to chronic hepatitis, cirrhosis and hepatocellula...

BACKGROUND Congenital dermal sinuses represent cutaneous depressions or tracts that are lined by stratified squamous epithelium. They communicate between the surface of the skin and deeper structures and may occur anywhere along the craniospinal axis. These sinuses are thought to result from abnormal separation of the cutaneous and neural ectoderm between the third and fifth week of intrauterin...

Wound healing plays an important role in protecting the human body from external infection. Cell migration and proliferation of keratinocytes and dermal fibroblasts are essential for proper wound healing. Recently, several studies have demonstrated that secondary compounds produced in plants could affect skin cells migration and proliferation. In this study, we identified a novel compound DK223...

background: beside various factors for producing diabetes, it seems that chronic hepatitis c, hiv/hcv co-infection, and anti-retroviral treatment especially including protease inhibitors may predispose to diabetes. this study conducted to determine prevalence of diabetes in hiv and hcv patients. methods: the registries of 150 hcv patients, 50 hiv patients and 90 hiv/hcv co-infected patients in ...

Accumulating evidence suggests a contribution of T cell-derived IL-17, IL-21 and IL-22 cytokines in skin immune homeostasis as well as inflammatory disorders. Here, we analyzed whether the cytokine-producing T lymphocytes could be induced by the different subsets of human skin dendritic cells (DCs), i.e., epidermal Langerhans cells (LCs), dermal CD1c(+)CD14(-) and CD14(+) DCs (DDCs). DCs were p...

<p class="abstract">Phacomatosis pigmentovascularis is a rare group of syndromes characterized by the co-existence vascular nevus and pigmentary with or without extracutaneous systemic involvement. The existing classifications phacomatosis are based on phenotypic characteristics. We report case pigmentovascularis, flammeus, anaemicus dermal melanocytosis manifestations. molecular basis ye...

evidence has shown that liver disease caused by hepatitis viruses can be more aggressive and severe in hiv infected subjects. therefore, the present cross-sectional study aimed to evaluate the seroprevalence of hdv infection among hiv/hbv co-infected clients in shiraz, southwest iran. in this study, 178 patients co-infected with hbv and hiv individuals were enrolled. the diagnosis of hiv infect...

IMPORTANCE Acellular dermal matrices have many current and potential applications, but their long-term safety has not been extensively studied. In particular, limited information exists regarding such materials' resistance to infection. OBJECTIVE To assess the resistance to microbial penetration of common acellular dermal matrix materials used in reconstruction after skin cancer excision, tre...

A model of Leishmania major infection in C57BL/6 mice has been established that combines two main features of natural transmission: low dose (100 metacyclic promastigotes) and inoculation into a dermal site (the ear dermis). The evolution of the dermal lesion could be dissociated into two distinct phases. The initial "silent" phase, lasting 4-5 wk, favored establishment of the peak load of para...

results migration of cells started on the fifth day. as a result of this migration, most cells were located on the surface of the scaffold and formed epiderm-like structure and some penetrated into the scaffold. by day 25, cells which had penetrated into the scaffold had various destinies such as becoming elongated spindle-shaped cells and creating blood vessel-like structures. conclusions adm ...