نتایج جستجو برای: depot
تعداد نتایج: 4391 فیلتر نتایج به سال:
The accumulation of fat in upper-body (abdominal) adipose tissue is associated with obesity-related cardiometabolic diseases, whereas lower-body (gluteal and femoral) fat may be protective. Studies suggest physiological and molecular differences between adipose depots and depot-specific cellular mechanisms of adipose expansion. We assessed in vivo cellular kinetics in subcutaneous adipose tissu...
Venom immunotherapy has proven a very effective method for the treatment of allergy to Hymenoptera venom. Aqueous instead of depot extracts are prevalently used for this immunotherapy. The advantage of using aqueous extracts has not been fully investigated. We made an open, non-controlled study on 45 subjects sensitized to either Apis mellifera or Vespula spp. Patients were assigned to either a...
Objective Recently, skin reactions to luteinizing hormone-releasing hormone (LH-RH) agonist therapy were reported after the 3-month depot type was released. We evaluate skin reactions to the 3-month depot type of LHRH agonist by questionnaires obtained from patients with prostate cancer who had been given a subcutaneous injection of LH-RH agonist. Materials and Methods A questionnaire regarding...
Vitamin D deficiency is highly prevalent in newly settled refugees in Western Australia (WA). If adherence to daily vitamin D therapy is problematic, depot therapy is a therapeutic alternative. The aim of this study was to compare daily versus depot treatment and factors influencing the therapeutic outcome. Newly settled refugees (n = 151) with 25(OH)D levels less than 78 nmol/L were randomised...
BACKGROUND Pituitary suppression by depot GnRH agonist may be excessive for ovarian stimulation in assisted reproduction technology. This study compares the efficacy of standard and half-dose depot triptorelin in a long protocol. METHODS A total of 180 patients were randomized into two groups using sealed envelopes. Pituitary desensitization was obtained in group 1 (90 patients) with half-dos...
Supply chain excellence has a real huge impact on business strategy. Building supply chains (SCs) as flexible system represents one of the most exciting opportunities to create value. This requires integrated decision making amongst autonomous chain partners with effective decision knowledge sharing among them. The key to success lies in knowing which decision has more impact on the supply chai...
In real-life logistics and distribution activities it is usual to face situations in which the distribution of goods has to be made from multiple warehouses or depots to the final customers. This problem is known as the Multi-Depot Vehicle Routing Problem (MDVRP), and it typically includes two sequential and correlated stages: (a) the assignment map of customers to depots, and (b) the correspon...
Three-month sustained-release triptorelin (11.25 mg) in the treatment of central precocious puberty.
OBJECTIVE Depot GnRH agonists are commonly used in the treatment of central precocious puberty (CPP). The triptorelin 11.25 mg 3-month depot, currently used in adult indications, had not previously been evaluated in CPP. DESIGN This was a multicenter, open-label, 12 month trial conducted in 64 CPP children (54 girls and 10 boys), treated quarterly. METHODS Children with a clinical onset of ...
The rapid advancements in information technologies and globalization change the way of distributing goods to customers. Many enterprises have multiple factories, warehouses, distribution centers strive for competitive efficiency operations minimize transportation costs. This study proposed mixed-integer programming (MIP) model multi-depot split-delivery vehicle routing problems (MDSDVRPs) with ...
This paper proposes two new distance-constrained capacitated vehicle routing problems (DCVRPs) to investigate for the first time, and study potential benefits in flexibly assigning start and end depots. The first problem, DCVRP Fix is an extension of the traditional symmetric DCVRP, with additional service and travel time constraints, minimization of the number of vehicles and flexible applicat...
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