DDT remains an important type of persistent organic pollutant (POP) in the environment of China. One of the current applications of DDT in China has been through antifouling paint for fishing ships as an active component. It has been estimated that approximately 5000 t of DDT was released into the Chinese coastal environment during the last two decades. Therefore, sediments in coastal fishing h...

Impregnated bednets can be considered a major tool for reducing Anopheles bites, malaria morbi dity and overall mortality. The resistance of Anopheles gambiae to pyrethroids used to impregnate bednets and curtains has already been noted in the urban area of Cotonou in Benin (18, 21). In this study, we wished to find out if the resistance observed in Cotonou is localized only in this town or is ...

We investigated the tissue-specific effects of dichlorodyphenyltrichloroethane (DDT) isomers in adult and suckling newborn mice, using a novel mouse line engineered to express a reporter of estrogen receptor transcriptional activity (ERE-tkLUC mouse). The DDT isomers p,p'-DDT [1,1,1-trichloro2,2-bis(p-chlorophenyl) ethane] and o,p'-DDT [1,1,1-trichloro-2(p-chlorophenyl)-2-(o-chlorophenyl) ethan...

For many decades, Botswana has been engaged in various malaria control activities that involved programmes that focused on the elimination of the malaria vector Anopheles ara‐ biensis, by using DDT and pyrethroids. Despite the numerous and continuous application of these insecticides, studies have shown that there is susceptibility of this vector to DDT and pyrethroids in Botswana. Natural inse...

(ITNs) and indoor residual spray (IRS) have made significant decrease in the number of malaria cases, but these efforts are subsided by the development and spread of insecticide resistance among major malaria vectors1. Currently, DDT and synthetic pyrethroids are used widely for IRS and ITNs throughout the malaria endemic countries including India, which insist unconditional need of regular mon...

Resistance of mosquitoes to insecticides is mainly attributed to their adaptation to insecticide-based vector control interventions. Although pesticides used in agriculture have been frequently mentioned as an additional force driving the selection of resistance, only a few studies were dedicated to validate this hypothesis. The objective of this study was to investigate the effect of exposure ...

BACKGROUND Pyrethroid insecticides, especially permethrin and deltamethrin, have been used extensively worldwide for mosquito control. However, insecticide resistance can spread through a population very rapidly under strong selection pressure from insecticide use. The upregulation of aldehyde dehydrogenase (ALDH) has been reported upon pyrethroid treatment. In Aedes aegypti, the increase in AL...

The status of resistance was investigated in Anopheles gambiae sensu lato and An. funestus (Diptera: Culicidae) mosquitoes from western Kenya to four classes of insecticides approved by World Health Organization for indoor residual spraying. The prevalence of the knockdown-resistance (kdr) mutation associated with resistance to pyrethroids and DDT was determined in An. gambiae s.l.. Standard Wo...

The status of resistance was investigated in Anopheles gambiae sensu lato and An. funestus (Diptera: Culicidae) mosquitoes from western Kenya to four classes of insecticides approved by World Health Organization for indoor residual spraying. The prevalence of the knockdown-resistance (kdr) mutation associated with resistance to pyrethroids and DDT was determined in An. gambiae s.l.. Standard Wo...