objective(s): according to the occupationally risk of infection in staff workers who have direct contact with mycobacterium species, we investigated their immunological parameters and compared with healthy purified protein derivative (ppd) negative volunteers.   materials and methods : we investigated 20 ppd positive volunteers working at tuberculin unit of razi vaccine and serum research insti...

introduction: multiple sclerosis (ms) has been recognized as a common neurodegenerative disease that occurs after an auto reactive t cells against myelin antigens.  demyelination and inflammation are the main features of this disease. the anti-inflammatory and neuroprotective roles of bone marrow-derived mesenchymal stem cells (bm-mscs) have been considered as a suitable treatment against autoi...

t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

in today’s advanced world resulting from the improvement of technology, societies tend to encounter a large number of problems and accidents. as we know, university’s security personnel are classified as shift workers and are exposed to health disturbing factors. the aim of this study was investigation of shift work disorders among security personnel of the hospitals affiliated to shiraz univer...

Background and Objectives: Shift working has the potential to negatively influence the quality of work life among nurses. The purpose of this study was to investigate the outbreak of shift work-related disorders and the relationship between shift work and job satisfaction in nurses of Ilam University’s subsidiary hospitals, in order to identify potential strategies for decreasing risk of health...

background: health workers ability to provide high quality care can be adversely affected by many factors such as sleep deprivation associated with shift work. the aim of this study was to compare sleep disorders among shift workers and non-shift workers in kermanshah hospital (2005) methods: at first, demographic information of the participants were gathered. 653 volunteers were divided into t...

Interleukin (IL)-17 is exclusively produced by CD4 helper T-cells upon activation. It most often acts as a pro-inflammatory cytokine, which stimulates the release of pro-inflammatory cytokines IL-6, IL-8, TNF-α, and granulocyte-macrophage colony-stimulating factor (GM-CSF). In this study, we studied the in-vitro IL-17 response to specific antigens and a variety of mitogens and compared the IL-1...

background: today, obesity is considered as a health problem that increases the risk of some diseases. therefore, identifying the effective factors on obesity is of great importance. shift work is one of the indicators for increased risk of obesity in society and also shift work may cause various health problems for workers in military organizations. the current study aimed to investigate the r...