This study was designed to elucidate the effect of ascorbic acid on salivary total antioxidant capacity in smokers. In this single blind crossover clinical trial, the whole unstimulated saliva of 30 smokers, who were randomly divided into two groups, was collected. In the first phase after the saliva collection, one group of patients took 500 mg of vitamin C powder, for 3 weeks. Then, saliva of...

The effect of topical disodium cromoglycate (DSCG) has been examined in 30 patients with chronic active proctitis using a double-blind crossover trial. Each treatment period was four weeks and patients were given DSCG 200 mg by enema twice daily and 100 mg orally three times each day. Twenty-six patients completed the trial successfully, 14 responded to DSCG treatment, two improved with placebo...

Methods Twenty-two males (n = 13) and females (n = 9) ages 20– 36 years (23.68 +/3.91), volunteered as subjects. Each subject performed two VO2max treadmill tests within two weeks of each other. Administration of the trials was double-blinded and randomized with half of the participants ingesting PRX1 during the first trial and PRX2 during their second trial with the product order being reverse...

Background Blood sampling is a usual and painful procedure on preterm infant. Repeating painful procedures may affect the process of normal brain development and Pain management is important for nurses. This study was conducted to evaluate and compare pain score in two sites of blood sampling in preterm infants. Materials and Methods Blood sampling is a usual and painful procedure on preterm in...

A double-blind controlled clinical trial of crossover design was conducted in 26 volunteers suffering from migraine. Of 20 subjects who completed the trial, 16 had fewer attacks on amitriptyline than on placebo. Amitriptyline was found to have the greatest effect in reducing attacks with a short warning and in which no specific cause could be recognized. It had least effect in attacks with a lo...

Different methods for analysing normally distributed data from a simple two-period, two-treatment crossover trial with SAS/STAT are explored. Special emphasis is given to trials in which some data from one of the two periods are missing. The size and the power of the statistical tests are investigated by simulating data under various scenarios. To select the most suitable method for a particula...

Background: Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low levels of constant via scalp electrodes to specifically targeted areas the brain. The effects tDCS on whole-body exercise performance has been interest in recent literature. purpose investigation was investigate if tDCS, administered Halo Sport, influences time trial trained cyclists, and...