نتایج جستجو برای: cirrhotic nodule

تعداد نتایج: 21135  

Journal: :Annals of hepatology 2013
Burak Suvak Serkan Torun Adnan Tas Yavuz Beyazit

AIM Ascitic fluid infection (AFI) consists primarily of two variants, namely, culture-negative neutrocytic ascites and spontaneous bacterial peritonitis (SBP). Mean platelet volume (MPV) has begun to be used as a simple and inexpensive indicator of inflammation in some diseases. We aimed to analyse whether platelet size alterations would be useful in predicting AFI in cirrhotic patients. MATE...

2016
Mariacarla Andreozzi Cristina Quintavalle David Benz Luca Quagliata Matthias Matter Diego Calabrese Nadia Tosti Christian Ruiz Francesca Trapani Luigi Tornillo Alfredo Fusco Markus H Heim Charlotte KY Ng Pierlorenzo Pallante Luigi M Terracciano Salvatore Piscuoglio

BACKGROUND HMGA1 is a non-histone nuclear protein that regulates cellular proliferation, invasion and apoptosis and is overexpressed in many carcinomas. In this study we sought to explore the expression of HMGA1 in HCCs and cirrhotic tissues, and its effect in in vitro models. METHODS We evaluated HMGA1 expression using gene expression microarrays (59 HCCs, of which 37 were matched with their...

2017
Carla Giménez-Garzó Juan José Garcés Amparo Urios Alba Mangas-Losada Raquel García-García Olga González-López Remedios Giner-Durán Desamparados Escudero-García Miguel Angel Serra Emilio Soria Vicente Felipo Carmina Montoliu

BACKGROUND AND AIMS The psychometric hepatic encephalopathy score (PHES) is the "gold standard" for minimal hepatic encephalopathy (MHE) diagnosis. Some reports suggest that some cirrhotic patients "without" MHE according to PHES show neurological deficits and other reports that neurological alterations are not homogeneous in all cirrhotic patients. This work aimed to assess whether: 1) a relev...

Journal: :Archives of surgery 1998
C C Wu S M Kang W M Ho J S Tang D C Yeh T J Liu F K P'eng

BACKGROUND The need for blood transfusion in cirrhotic liver resection is difficult to determine because of inaccurate estimation of operative blood loss. Moreover, blood transfusion is detrimental to cirrhotic patients. OBJECTIVE To investigate the predictors and limitations of hepatectomy without blood transfusion for cirrhotic patients. DESIGN Retrospective study. SETTING University ho...

2017
Kyung-Hwa Shin In-Suk Kim Hyun Ji Lee Hyung-Hoi Kim Chulhun L. Chang Young Mi Hong Ki Tae Yoon Mong Cho

BACKGROUND The aims of this study were to investigate the parameters of thromboelastography (TEG) for evaluating coagulopathy and to reveal an association with disease severity and/or transfusion requirement in patients with chronic liver disease (CLD) in a clinical laboratory setting. METHODS We enrolled two groups of adult patients with cirrhotic (N=123) and non-cirrhotic liver disease (N=5...

2015
Frank E. Uschner Ganesh Ranabhat Steve S. Choi Michaela Granzow Sabine Klein Robert Schierwagen Esther Raskopf Sebastian Gautsch Peter F. M. van der Ven Dieter O. Fürst Christian P. Strassburg Tilman Sauerbruch Anna Mae Diehl Jonel Trebicka

Liver cirrhosis but also portal vein obstruction cause portal hypertension (PHT) and angiogenesis. This study investigated the differences of angiogenesis in cirrhotic and non-cirrhotic PHT with special emphasis on the canonical (Shh/Gli) and non-canonical (Shh/RhoA) hedgehog pathway. Cirrhotic (bile duct ligation/BDL; CCl4 intoxication) and non-cirrhotic (partial portal vein ligation/PPVL) rat...

Journal: :The Journal of pharmacology and experimental therapeutics 2007
Massimo Bolognesi David Sacerdoti Anna Piva Marco Di Pascoli Francesca Zampieri Santina Quarta Roberto Motterlini Paolo Angeli Carlo Merkel Angelo Gatta

Large-conductance calcium-activated potassium channels (BK(Ca)s) are important regulators of arterial tone and represent a mediator of the endogenous vasodilator carbon monoxide (CO). Because an up-regulation of the heme oxygenase (HO)/CO system has been associated with mesenteric vasodilatation of cirrhosis, we analyzed the interactions of BK(Ca) and of HO/CO in the endothelium-dependent dilat...

2011
Wan‐dong Hong Le‐mei Dong Zen‐cai Jiang Qi‐huai Zhu Shu‐Qing Jin

OBJECTIVES Recent guidelines recommend that all cirrhotic patients should undergo endoscopic screening for esophageal varices. That identifying cirrhotic patients with esophageal varices by noninvasive predictors would allow for the restriction of the performance of endoscopy to patients with a high risk of having varices. This study aimed to develop a decision model based on classification and...

Journal: :The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2016
Wael A Abbas Soheir M Kasem Ahmed Amal M Abdel Aal Amal A Mahmoud Mohamed O Abdelmalek Mohamed A Mekky Mohamed A A Abozaid Ahmed K Ibrahim

BACKGROUND/AIMS Cirrhotic cardiomyopathy (CCM) is defined as an abnormal heart structure and function in cirrhotic patients. CCM includes systolic and diastolic dysfunction, electrophysiological abnormalities, and structural changes, both microscopic and macroscopic. Currently, there is no one diagnostic test that can identify patients with CCM. Evaluation of the validity of galactin-3 and brai...

2013
Chao Dong Han-Jun Li Shi Chang Hui-Jun Liao Zhi-Peng Zhang Peng Huang Hui-Huan Tang

BACKGROUND/AIMS We aimed to investigate the correlation between a disintegrin and metalloprotease with thrombospondin motif 2 (ADAMTS-2) and transforming growth factor-β1 (TGF-β1) in clinical human cirrhotic tissues. METHODS The liver tissues of 24 patients (16 cases with cirrhotic portal hypertension as the cirrhosis group and eight cases with healthy livers as the normal group) were collect...

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