today, chronic viral hepatitis is considered as a public health problem in the world. totally, 5% of the world population, especially in asia and africa suffer from this problem. the prevalence of acute hepatitis in america is 0.1-0.2 percent, 50% of those with hepatitis c (hcv) and 5-10% of them with hepatitis b (hcv) develop chronic hepatitis. determining hbv and hcv genotypes is important to...

AIM To evaluate portalsystemic hemodynamic changes in chronic severe hepatitis B. METHODS Hemodynamic parameters included portal vein diameter (PVD), portal vein peak velocity (PVPV), portal vein volume (PVV), spleen length (SPL), spleen vein diameter (SPVD), spleen vein volume (SPVV) and umbilical vein recanalization. They were measured by Color Doppler ultrasonography in 36 patients with ch...

Correspondence to: Dr P Ferenci, Clinic of Internal Medicine IV, Department of Gastroenterology and Hepatology, University of Vienna, Wahringer Gurtel 18-20, A-1090 Wien, Austria. Abstract Interferon is currently considered to be the only accepted effective treatment for chronic viral hepatitis. A history of the treatment of chronic hepatitis B and C before the use of interferon is presented he...

'die presence anil significance of hepatitis c virus infection among patients with chronic renal failure (crf) on hemodialysis and renal transplant recipient were evaluated a pcrioil of 30 months. a total of 125 patients, comprising 25 recieving chronic hemodialysis, 47 renal transplant candidates and 5.1 renal transplant recipients, were studied with a second generation immunoassay (elisa ii)....

conclusions the results indicated that there was a positive association between susceptibility to chronic hbv infection and tnf-α polymorphism. in addition, hbv patients carrying -308 gg, -857 cc, and -863 aa genotypes with lower serum levels of tnf-α had an increased risk of infection. background the host genetic background regulates the natural history of chronic hepatitis b virus (hbv) infec...

conclusions our study comprehensively explored the predictive factors of therapeutic effect of administered drugs and analyzed viral relapse during a six-months to six-year follow-up period from china. the svr may not be the perfect endpoint of hcv therapy in chinese people; we recommend 48 weeks after treatment withdrawal as the suitable time point. patients and methods we retrospectively anal...

background egypt has one of the highest (16-8%) prevalence rates of hcv infection in the world. approximately 90% of egyptian hcv isolates belong to a single subtype (4a), which responds less successfully to interferon therapy than other subtypes. studies comparing the efficacy and safety of pegifn alfa-2a and pegifn alfa-2b in treatment-naive hcv-infected patients have shown conflicting result...

conclusions family history as well as baseline bilirubin, ast and hbv dna levels can predict early virological response. the model provides a better tool for response prediction based on the four prognostic factors. results negative family history of hbv infection (p = 0.000235), baseline higher serum tbil (p = 0.038714) and ast (p = 0.020684) concentrations, and lower level of hbv-dna (p = 0.0...

introduction: hepatitis b is a potentially life-threatening infection that causes acute infection and chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma (hcc). interleukin-12 (il12) is responsible for activation of th1 immune responses, leading to possible clearance of hbv infection from the host’s body. the host’s immune-genetic background plays an important role in t...

introduction: the hepatitis b is a viral infection that causes a big problem globally. about 2 billion people worldwide are infected and there are now about 400 million hbv-dna carriers around the world. hbv infection is the ninth cause of death worldwide and infects about 350 million new cases each year in the world. hbv-dna can be spotted in different body secretions and fluids, including ser...