Background: Recently, the Flattening Filter Free (FFF) beams, which allow a dose rate increase of up to four times compared to the normal dose rate, have been incorporated into radiation therapy machines. The aim of this study is to evaluate antitumor activity in hypoxic cells irradiated with different dose rates using FFF beams and to identify the casual mechanism for cellular damage during ir...

Objective: This study was planned to investigate whetherCoriandrum sativum (C. sativum) is capable of protecting neurons against glucose/serum deprivation (GSD)-induced cytotoxicity. Material and Methods: The PC12 cells were cultivated for 24 h in standard media (high-glucose DMEM containing Fetal Bovine Serum) or for 6 h in GSD condition (glucose-free DMEM, without serum) in the absence or pr...

Objective(s): Binary hybrids of chitosan-zeolite have many interesting applications in separation and bacteriostatic activity. Materials and Methods: Template free ZSM-5 zeolite was synthesized by hydrothermal method, physical hydrogels of nano chitosan in the colloidal domain were obtained in the absence of toxic organic solvent and then nano chitosan/ZSM-5 hybrid composites with nano chitosan...

objective(s): in the current study antioxidant capacities of five different extracts of artemisia ciniformis aerial parts were evaluated by cell-free methods. then seven fractions of the potent extract were selected and their antioxidant capacity was assayed by cell free and cell based methods. materials andmethods: antioxidant ability was measured using the: 2, 2-diphenyl-1-picrylhydrazyl (dpp...

Assessment of the cellular effects of natural and/or synthetic products is one of the major goals in biological experiments. This assessment may be conducted at different levels; cellular viability, cellular biological activity, and cellular structure and morphology. Different assays are available for any of above purposes. It is becoming of a routine exercise to apply any of these assays, and ...

The carbohydrate-binding proteins galectin-1 and galectin-3 are found in nucleus of cells. Using a cell-free assay, depletion and reconstitution experiments have documented that these two proteins are required factors in pre-mRNA splicing. Thiodigalactoside, which binds to both galectins, inhibited the splicing reaction whereas cellobiose, which binds neither protein, failed to yield the same e...

Abstract Easy, quantitative measures of biomolecular heterogeneity and high-stratified phenotyping are needed to identify characterise complex disease processes at the single-cell level, as well predict cell fate. Here, we demonstrate how Raman spectroscopy can be used in difficult-to-assess case clonal, bone-derived mesenchymal stromal cells (MSCs) MSC lines group these according biological fu...

objective: this study was planned to investigate whethercoriandrum sativum (c. sativum) is capable of protecting neurons against glucose/serum deprivation (gsd)-induced cytotoxicity. material and methods: the pc12 cells were cultivated for 24 h in standard media (high-glucose dmem containing fetal bovine serum) or for 6 h in gsd condition (glucose-free dmem, without serum) in the absence or pre...