نتایج جستجو برای: caspase 7
تعداد نتایج: 675164 فیلتر نتایج به سال:
Ultraviolet B radiation (UVB) is a ubiquitous environmental toxin that causes extensive skin damage resulting in inflammation, photoaging and cancer. UVB known to induce inflammasome activation sterile inflammation associated with cytokine release (e.g. IL-1β, IL-18) immune cell infiltration. We developed circularly permutated luciferase reporters for caspase-1 assess by vitro vivo. HaCaT kerat...
OBJECTIVE To explore the neuroprotective mechanism of Ginkgolides or Ginkgo flavonoids on the TNF-α induced apoptosis of cultured rat hippocampal neurons. MATERIALS AND METHODS Primary hippocampal neurons were isolated from rat brains and cultured with (model group) or without (control group) addition of tumor necrosis factor-α (TNF-α, final concentration of 40 ng/ml) to induce apoptosis. TNF...
Despite the fact that the chromosomal passenger complex is well known to regulate kinetochore behavior in mitosis, no functional link has yet been established between the complex and kinetochore structure. In addition, remarkably little is known about how the complex targets to centromeres. Here, in a study of caspase-8 activation during death receptor-induced apoptosis in MCF-7 cells, we have ...
AIM To investigate the role of valproic acid (VPA), a class I selective histone deacetylase inhibitor, on Michigan Cancer Foundation (MCF)-7 breast cancer cells, named and explore its possible molecular mechanism. METHODS MCF-7 cells were cultured with sodium valproate (0. 5-4.0 mmol/L) for 24 h, 48 h, and 72 h in vitro, respectively. The cell viability, apoptosis, and cell cycle were examine...
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