Famotidine has been the most widely used drug for the treatment of peptic ulcer for many decades. The present investigation concerns the development and evaluation of floating tablets of famotidine which, after oral administration, are designed to prolong the gastric residence time, increase drug bioavailability and target the gastric ulcer. A floating drug delivery system (FDDS) was developed ...

Objective: The objective of the present work was to formulate a gastroretentive dosage form of Valacyclovir, an anti viral drug. Methods: Valacyclovir gastroretentive mucoadhesive tablets were prepared using polymers such as Carbopol 974P and hydroxy propyl methyl cellulose (HPMC) K4M, in different proportions by wet granulation technique. Compatibility studies were performed by FTIR spectrosco...

Hand sanitizer adalah antiseptik yang efektif karena mudah untuk dibawa kemanapun. biasanya mengandung 60-80% senyawa alkohol. Penggunaan alkohol secara terus menerus dapat mengakibatkan iritasi dan kulit kering. Alkohol dalam hand dikurangi dengan cara menambahkan bahan alami bersifat antiseptik. Alternatif digunakan tanaman lidah buaya. Daging buaya flavonoid, saponin, tanin, gliserin polifen...

In recent years there has been relatively little attention given to the question of the extent to which bacteria occur within muscle tissues. Although the available evidence has been far from conclusive, the ubiquitous presence of an intramuscular bacterial population which includes pathogenic species has often been assumed. The following passage by lngram & Dainty (1 971) gives an account of t...

*Correspondence: [email protected] 1Luleå University of Technology, Luleå, 971 87, Sweden 2Narvik University College, P.O. Box 385, Narvik, 8505, Norway Full list of author information is available at the end of the article Abstract We consider the q-analog of the Riemann-Liouville fractional q-integral operator of order n ∈ N. Some new Hardy-type inequalities for this operator are proved and dis...

Patricia Miretzky Centro de Estudios Transdiciplinarios del Água, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Chorroarín 280, Buenos Aires (1427) Argentina Márcia Cristina Bisinoti e Wilson F. Jardim* Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13084-971 Campinas SP, Brasil Júlio César Rocha Instituto de Química, Universidade Estadual Paulista, CP 355, ...

A mucoadhesive drug delivery system for local delivery of metronidazole through vaginal route was formulated. Films were prepared by solvent evaporation method using various compositions of Carbopol, hydroxypropylmethylcellulose, chitosan, Polyox and propylene glycol. The films were evaluated for their weight, thickness, surface pH, folding endurance, mechanical, drug content uniformity, in vit...

The objective of this study was to develop intranasal nanoemulsion and gel formulations for rizatriptan benzoate for prolonged action. Nanoemulsion formulations were prepared by constructing pseudo-ternary phase diagrams using lipophilic and hydrophilic surfactants and water. Various mucoadhesive agents were tried out to form thermo-triggered mucoadhesive nanoemulsions. Mucoadhesive gel formula...

In this issue of Genes & Development, Urbach and colleagues (pp. 971-982) provide compelling data suggesting a role for LIN28 in the pathogenesis of a significant percentage of Wilms tumors. These data extend our insights in the genetics underlying Wilms tumor development and emphasize the importance of stemness and microRNA-mediated processes in the origins of these tumors.

Abstract The review presents current research results for Carbopol-based microgels as yield-stress materials, covering three aspects: chemical, physical and rheological. Such a joint three-aspect study has no analog in the literature. chemical aspects of Carbopol polymers are presented terms cross-linking polymerization acrylic acid, their molecular structure, microgel formulation, polyacid dis...