PURPOSE A Multiparticulate system of Mebendazole was developed for colon targeted drug delivery by using natural polysaccharides like Chitosan and Sodium-alginate beads. METHODS Chitosan microspheres were formulated by using Emulsion crosslinking method using Glutaraldehyde as crosslinking agent. Sodium-alginate beads were formulated by using Calcium chloride as gelling agent. Optimization fo...

Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) have been shown to generate bone in vivo by executing an endochondral programme. This may hinder the use of MSCs for articular cartilage regeneration, but opens the possibility of using engineered cartilaginous tissues for large bone defect repair. Hydrogels may be an attractive tool in the scaling-up of such tissue engineered...

Three-dimensional (3D) printing is an emerging technology for the fabrication of scaffolds to repair/replace damaged tissue/organs in tissue engineering. This paper presents our study on 3D printed alginate scaffolds treated with phosphate buffered saline (PBS) and polyethyleneimine (PEI) coating and their impacts on the surface morphology and cellular response of the printed scaffolds. In our ...

For much of the Caribbean, plastic pollution and great Atlantic Sargassum belt has led to significant regional loss. To elevate these problematic areas, we present a novel calcium alginate bioplastic process from lens techno-economic life cycle assessments.

Anionic surfactants are the most widely exploited chemical surfactants, which are being incorporated into majority of detergents and cleaning products used for household and industrial applications. Linear alkylbenzene sulfonates (LAS) is one of the major xenobiotic anionic surfactants. Biodegradation is an effective process to reduce the amount of surfactants released in the environment. In th...

Calcium alginate beads covalently linked with alpha-cyclodextrin (alpha-CD-alginate beads) were prepared and examined for their ability to serve as a supporting matrix for bacterial degradation of nonylphenol, an endocrine disruptor. Column chromatographic experiment using alpha-CD-alginate beads with diameter of 657+/-82 microm and with degree of CD substitution of 0.16 showed a strong affinit...

Two samples of acid-hydrolyzed nanocellulose and two samples of TEMPO-oxidized nanocellulose were separately prepared from cotton liner pulp and microcrystalline cellulose, and dispersed in water. Sodium alginate that was extracted from brown seaweed was dissolved in the nanocellulose suspensions and wet spun in a calcium chloride bath to form four kinds of alginate/nanocellulose composite fibe...

Purpose: To evaluate imbibition and syneresis in four commercially available irreversible hydrocolloid (alginate) impression materials at different time intervals (10, 20 and 30 minutes). Materials and methods: Eighty samples of four commercially available irreversible hydrocolloid (alginate) impression materials Algitex (DPI, Mumbai), Plastalgin (Septodont, Cedex, France), Zelgan 2002 (Dentspl...

microencapsulation as one of the most modern methods has remarkable effects on probiotic survival. in this study lactobacillus casei (atcc 39392) and bifidobacterium bifidum (atcc 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and were incubated in simulated gastric juice (along with pepsin, ph=1.5) and simulated intestina...

Extracellular keratinase isolated from Aspergillus flavus K-03 was immobilized on calcium alginate. The properties and reaction activities of free and immobilized keratinase with calcium alginate were characterized. The immobilized keratinase showed proteolytic activity against soluble azo-casein and azo-keratin, and insoluble feather keratin. Heat stability and pH tolerance of keratinase were ...